Fukuchi Takeo

Ando Takumi, Terashima Hiroko, Tsuboi Kotaro, Oizumi Kazuaki, Yoshida Hiromitsu, Nozaki Yohei et al.

This study found glaucoma, secondary ERM, ICG use, and male sex increase microscotoma risk after ERM surgery. Preoperative visual field thresholds can predict this risk, guiding surgical planning.

Igarashi Ryoko, Ochiai Shun, Togano Tetsuya, Sakaue Yuta, Suetake Aki, Iikawa Ryu et al.

OCTA-measured foveal avascular zone (FAZ) area in glaucoma patients correlated with retinal nerve damage and visual field loss, suggesting FAZ enlargement reflects disease severity and could aid monitoring.

Chernyshova Kseniia, Inoue Keiichi, Yamashita Shun-Ichi, Fukuchi Takeo, Kanki Tomotake

Glaucoma-associated OPTN mutations were studied for their impact on mitophagy. Unlike ALS mutations, glaucoma mutations did not impair mitophagy, suggesting glaucoma's cause isn't via mitophagy defects.

Aihara Makoto, Adachi Misato, Matsuo Hiroshi, Togano Tetsuya, Fukuchi Takeo, Sasaki Noriyuki

This study found brinzolamide/timolol fixed combination was non-inferior to dorzolamide/timolol in lowering IOP for glaucoma patients already on prostaglandin, suggesting it's a safe and effective additive treatment.

Kunimatsu-Sanuki Shiho, Iwase Aiko, Araie Makoto, Aoki Yuki, Hara Takeshi, Fukuchi Takeo et al.

This study found advanced glaucoma patients with inferior visual field loss (13-24 degrees) had more simulated driving collisions with oncoming cars, highlighting this specific field defect as a collision risk factor.

Fukuchi Takeo, Yoshino Takaiko, Sawada Hideko, Seki Masaaki, Togano Tetsuya, Tanaka Takayuki et al.

This study found higher follow-up IOP correlated with faster visual field progression in high-tension glaucoma, while larger IOP fluctuations correlated with faster progression in normal-tension glaucoma. Monitoring both is crucial for prognosis.

Takano Yoshimasa, Shi Dong, Shimizu Ai, Funayama Tomoyo, Mashima Yukihiko, Yasuda Noriko et al.

This study found specific TLR4 gene variations are linked to primary open-angle, normal-tension, and exfoliation glaucoma in Japanese individuals, suggesting their role in disease development.

Seki Masaaki, Fukuchi Takeo, Ueda Jun, Suda Kieko, Nakatsue Tomoko, Tanaka Yoko et al.

Cataract surgery in nanophthalmic eyes significantly deepens the anterior chamber and widens the angle, potentially lowering intraocular pressure. This suggests a beneficial role for glaucoma management.

Sawada Hideko, Fukuchi Takeo, Abe Haruki

This study found that glaucoma patients' quality of life correlated with visual field loss, with the VFI slightly outperforming MD, especially in the better-seeing eye.

Sawada Hideko, Fukuchi Takeo, Tanaka Takayuki, Abe Haruki

This study found higher TNF-alpha in aqueous humor of glaucoma patients, especially exfoliation glaucoma, suggesting inflammation's role in glaucoma progression.

Funayama Tomoyo, Mashima Yukihiko, Ohtake Yuichiro, Ishikawa Karin, Fuse Nobuo, Yasuda Noriko et al.

This study found specific genetic variants and interactions in OLFM2 and OPTN genes are associated with open-angle glaucoma in Japanese patients, suggesting a polygenic cause.

Inagaki Yoko, Mashima Yukihiko, Funayama Tomoyo, Ohtake Yuichiro, Fuse Nobuo, Yasuda Noriko et al.

This study found PON1 gene polymorphisms influenced age at diagnosis in normal-tension glaucoma and intraocular pressure in open-angle glaucoma patients, suggesting genetic factors modify disease features.