Higashide Tomomi

Miki Atsuya, Araie Makoto, Leung Christopher Kai Shun, Nishigaki Masashi, Murata Hiroshi, Kikawa Tsutomu et al.

This study found that in glaucoma patients, the extent of retinal nerve fiber layer defects detected by ROTA was associated with optic nerve head gamma zone area, suggesting this structural change reflects axonal damage.

Enomoto Nobuko, Saito Hitomi, Araie Makoto, Kambayashi Mitsuki, Murata Hiroshi, Kikawa Tsutomu et al.

This study found deep ONH structures in healthy eyes correlate with scleral canal size and other factors, crucial for distinguishing normal from glaucomatous changes.

Higashide Tomomi, Udagawa Sachiko, Yamashita Yoko, Tsuchiya Shunsuke, Okuda Tetsuhiko, Kadonosono Kazuaki et al.

Glaucoma patients undergoing ERM surgery can experience significant, late visual acuity loss, especially with worse preoperative central vision and early postoperative central visual field decline, highlighting the need for long-term monitoring.

Hirooka Kazuyuki, Higashide Tomomi, Sakaguchi Kimikazu, Udagawa Sachiko, Sugiyama Kazuhisa, Oki Kenji et al.

This study found 11.8% of primary aldosteronism patients have normal-tension glaucoma, a significantly higher prevalence than controls, suggesting PA is an independent risk factor for NTG.

Kambayashi Mitsuki, Saito Hitomi, Araie Makoto, Enomoto Nobuko, Murata Hiroshi, Kikawa Tsutomu et al.

This study found that deep optic nerve structures, like lamina cribrosa depth and scleral canal shape, significantly influence both BMO-MRW and pRNFLT, highlighting their complex relationship in healthy eyes.

Saito Hitomi, Ueta Takashi, Araie Makoto, Enomoto Nobuko, Kambayashi Mitsuki, Murata Hiroshi et al.

This study found Bergmeister papilla strongly predicts more severe prelaminar schisis in both healthy and glaucomatous eyes, suggesting traction. PLS severity also correlated with glaucoma-related optic nerve head structures.

Asaoka Ryo, Sakata Rei, Yoshitomi Takeshi, Iwase Aiko, Matsumoto Chota, Higashide Tomomi et al.

This NTG study found different risk factors for progression in superior (IOP fluctuation) and inferior (BMI, myopia, cup-to-disc, disc hemorrhage) optic nerve halves, guiding tailored management.

Takemori Hayato, Higashide Tomomi, Kobayashi Akira, Yokogawa Hideaki, Sugiyama Kazuhisa

This study found prior trabeculectomy, post-DSAEK glaucoma treatment, and pupillary block significantly increase endothelial cell loss and graft failure risk, highlighting glaucoma's impact on corneal transplant outcomes.

Saito Hitomi, Kambayashi Mitsuki, Araie Makoto, Murata Hiroshi, Enomoto Nobuko, Kikawa Tsutomu et al.

This study found that longer axial length in healthy myopic eyes is associated with specific optic nerve head structural changes, including misalignment, choroid thinning, and scleral bowing, which is crucial for distinguishing myopia from glaucoma.

Nakazawa Kazuki, Higashide Tomomi, Tsuchiya Shunsuke, Shioya Satomi, Okayama Masahiko, Sugiyama Kazuhisa

This study found higher ambulatory blood pressure and certain ocular factors are linked to greater nocturnal and variable 24-hour IOP-related contact lens sensor readings in untreated glaucoma patients, suggesting these influence IOP fluctuations.

Mambo Yuki, Higashide Tomomi, Ohkubo Shinji, Udagawa Sachiko, Yamashita Yoko, Tsuchiya Shunsuke et al.

This study found Tenon advancement in fornix-based trabeculectomy significantly reduced bleb-related infections without compromising surgical success, offering a safer glaucoma surgery option.

Okayama Masahiko, Tsuchiya Shunsuke, Higashide Tomomi, Udagawa Sachiko, Yamashita Yoko, Shioya Satomi et al.

This study found corneal hysteresis varies diurnally, being higher at night in both glaucoma patients and healthy individuals, suggesting corneal viscoelastic properties fluctuate independently of IOP.

Takamatsu Yuki, Higashide Tomomi, Takeshima Satoshi, Sasaki Makoto, Manbo Yoshimi, Udagawa Sachiko et al.

Trabeculectomy reduced IOP, increasing macular choroidal thickness and blood flow. Vascular thickness correlated with blood flow, while interstitial thickness correlated with IOP changes, showing differential choroidal response.

Tsuchiya Shunsuke, Higashide Tomomi, Udagawa Sachiko, Sugiyama Kazuhisa

Vitrectomy for ERM can worsen central visual fields in glaucoma patients, especially in outer arcuate areas. Pre-existing worse VF and thinner GCC are key risk factors, guiding surgical counseling.

Shioya Satomi, Higashide Tomomi, Tsuchiya Shunsuke, Simon-Zoula Sonja, Varidel Thierry, Cerboni Sacha et al.

A contact lens sensor combined with single IOP readings identified glaucoma patients whose pressure exceeded diagnostic thresholds, helping reclassify those misdiagnosed as normal tension glaucoma without 24-hour tonometry.

Takemoto Daisuke, Higashide Tomomi, Ohkubo Shinji, Udagawa Sachiko, Sugiyama Kazuhisa

Macular GCL/IPL thickness asymmetry, measured by OCT, effectively detects preperimetric glaucoma, outperforming average thickness measurements. This aids early glaucoma diagnosis.

Ye Yunyan, Dinh Duong Tung Anh, Saito Kengo, Shinmyo Yohei, Ichikawa Yoshie, Higashide Tomomi et al.

This study developed a tissue clearing method to visualize intact retinal structures in mice and ferrets. This allows detailed, whole-eye imaging for glaucoma and other eye disease research, aiding therapy evaluation.

Yuasa Yuki, Sugimoto Yosuke, Hirooka Kazuyuki, Ohkubo Shinji, Higashide Tomomi, Sugiyama Kazuhisa et al.

Trabeculectomy with mitomycin C effectively lowered IOP and medication use in glaucoma patients, even with normal pre-operative pressures, showing good efficacy and few complications over 5 years.

Yamada Yutaro, Higashide Tomomi, Udagawa Sachiko, Takeshima Satoshi, Sakaguchi Kimikazu, Nitta Koji et al.

This study found that asymmetric optic nerve head blood flow strongly correlates with asymmetric visual field loss in glaucoma, suggesting blood flow differences contribute to varied disease severity between eyes.

Takeshima Satoshi, Higashide Tomomi, Kimura Masayo, Udagawa Sachiko, Yamada Yutaro, Takemoto Daisuke et al.

Trabeculectomy in glaucoma patients increased optic nerve head blood flow stability (higher BOS, lower RI) despite unchanged overall flow (MBR), suggesting improved microcirculation from IOP reduction.

Higashide Tomomi, Nishino Tsubasa, Sakaguchi Kimikazu, Yamada Yutaro, Sugiyama Kazuhisa

This study found trabeculectomy with MMC causes corneal endothelial cell loss, significantly worse in exfoliation and uveitic glaucoma, and older patients, highlighting key risk factors for corneal health.

Sakata Rei, Yoshitomi Takeshi, Iwase Aiko, Matsumoto Chota, Higashide Tomomi, Shirakashi Motohiro et al.

This study found that untreated Japanese normal-tension glaucoma patients have a high 5-year progression rate (66%). Disc hemorrhage, IOP fluctuation, and larger cup-to-disc ratio significantly predict progression, highlighting key risk factors.

Wada Yasushi, Higashide Tomomi, Nagata Atsushi, Sugiyama Kazuhisa

Topical ripasudil increased optic nerve head blood flow in normal rats, suggesting it could improve ocular perfusion in glaucoma patients, independent of IOP changes.

Sakaguchi Kimikazu, Higashide Tomomi, Udagawa Sachiko, Ohkubo Shinji, Sugiyama Kazuhisa

Studying glaucoma, peripapillary RNFL vessel density showed stronger, more consistent sectoral structure-function relationships than RNFL thickness. This suggests vessel density may be a superior structural biomarker.

Wada Yasushi, Higashide Tomomi, Nagata Atsushi, Sugiyama Kazuhisa

This study found rat optic nerve head blood flow, measured by LSFG, increases from 10-19 weeks then stabilizes, showing regional differences. This offers a reliable method for tracking ONH blood flow changes.