Takeda Hisashi

Nakatani Yusuke, Higashide Tomomi, Ohkubo Shinji, Takeda Hisashi, Sugiyama Kazuhisa

Cataract removal slightly increases OCT-measured ganglion cell complex and retinal nerve fiber layer thickness. Segmentation errors are more common in GCC measurements with cataracts, highlighting the need for careful interpretation.

Nakatani Yusuke, Higashide Tomomi, Ohkubo Shinji, Takeda Hisashi, Sugiyama Kazuhisa

SD-OCT macular and RNFL parameters were studied for early glaucoma detection. Macular parameters showed comparable diagnostic power and reproducibility to RNFL, offering valuable detection for early disease.

Gao Yanlin, Sakurai Mayumi, Takeda Hisashi, Higashide Tomomi, Kawase Kazuhide, Sugiyama Kazuhisa

This study found specific adrenergic receptor gene variations are linked to different diurnal IOP levels in Japanese NTG patients, suggesting these genes may influence untreated IOP.

Saito Yoshiaki, Higashide Tomomi, Takeda Hisashi, Murotani Eiji, Ohkubo Shinji, Sugiyama Kazuhisa

This study found that after intravitreal bevacizumab for anterior segment neovascularization, recurrence is common; however, trabeculectomy significantly reduced recurrence, suggesting its clinical benefit for these high-risk patients.

Saito Yoshiaki, Higashide Tomomi, Takeda Hisashi, Ohkubo Shinji, Sugiyama Kazuhisa

Preoperative bevacizumab improved trabeculectomy success and reduced bleeding in neovascular glaucoma, suggesting it's a valuable adjunct to improve surgical outcomes for these complex patients.

Nagata Atsushi, Higashide Tomomi, Ohkubo Shinji, Takeda Hisashi, Sugiyama Kazuhisa

OCT accurately quantified rat retinal nerve fiber layer thinning after optic nerve crush, demonstrating its utility for preclinical glaucoma research.

Ohkubo Shinji, Takeda Hisashi, Higashide Tomomi, Sasaki Tsugihisa, Sugiyama Kazuhisa

This study compared HRT II and stereoscopic photography for glaucoma screening. Photography showed higher sensitivity than HRT II, but both are useful for community glaucoma detection.

Kawaguchi Ichiro, Higashide Tomomi, Ohkubo Shinji, Takeda Hisashi, Sugiyama Kazuhisa

SLO effectively imaged rat retinal nerve fiber layer (RNFL) degradation after optic nerve crush. It quantitatively tracked RNFL thinning, demonstrating its utility for in vivo glaucoma research.

Higashide Tomomi, Kawaguchi Ichiro, Ohkubo Shinji, Takeda Hisashi, Sugiyama Kazuhisa

A scanning laser ophthalmoscope (SLO) effectively imaged and counted rat retinal ganglion cells (RGCs) in vivo, tracking their loss after optic nerve injury. This offers a valuable tool for monitoring RGC changes in glaucoma models.