Hollitt Georgina L

Hollitt Georgina L, Cohen-Woods Sarah, Siggs Owen M, Craig Jamie E, Souzeau Emmanuelle

49% of eligible individuals over 50 years old took polygenic risk tests for glaucoma. Family history, urban residence, and education predicted uptake. This provides crucial real-world insight for implementing genetic risk stratification in clinical practice.

Kolovos Antonia, Qassim Ayub, Hassall Mark M, Marshall Henry N, Schmidt Joshua, Nguyen Thi Thi et al.

Polygenic risk scores for glaucoma, IOP, and VCDR stratify glaucoma risk and severity in pseudoexfoliation patients, identifying those prone to earlier diagnosis and worse outcomes, aiding personalized management.

Hollitt Georgina L, Keane Miriam C, Nguyen Thi T, Hassall Mark M, Siggs Owen M, Craig Jamie E et al.

Australian healthcare professionals, despite low familiarity with glaucoma polygenic risk testing, showed positive attitudes towards its use, highlighting a critical need for education to support clinical implementation.

Berry Ella C, Marshall Henry N, Mullany Sean, Torres Santiago Diaz, Schmidt Joshua, Thomson Daniel et al.

This study found that greater physical activity is associated with slower macular thinning in glaucoma and thicker maculae overall, suggesting exercise may offer neuroprotection for the retina.

Hollitt Georgina L, Siggs Owen M, Ridge Bronwyn, Keane Miriam C, Mackey David A, MacGregor Stuart et al.

This study found strong interest (71.3%) in glaucoma genetic risk assessment among unaffected individuals, particularly those concerned about the disease or proactive about eye health. This supports integrating polygenic risk scores into clinical practice.

Marshall Henry, Mullany Sean, Han Xikun, Berry Ella C, Hassall Mark M, Qassim Ayub et al.

This study found a genetic link between cardiovascular disease risk and predominant macular retinal thinning in early glaucoma, suggesting systemic vascular health influences glaucoma presentation.