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The prostaglandin transporter OATP2A1 is expressed in human ocular tissues and transports the antiglaucoma prostanoid latanoprost.
Kraft Michaela E, Glaeser Hartmut, Mandery Kathrin, König Jörg, Auge Daniel, Fromm Martin F et al.
Invest Ophthalmol Vis SciMay 201050 citationsBasic Science
This study found OATP2A1 transports latanoprost acid and is highly expressed in human ocular tissues, suggesting it's crucial for latanoprost's intraocular action and may explain variable patient responses.