Lee Andrew G

Maheshwari Akash, Laylani Noor, Siliezar Pamela Davila, Lee Andrew G

A case showed psychogenic polydipsia can trigger acute angle closure crisis, likely via choroidal expansion or osmotic changes, highlighting a novel risk factor for vision loss.

Brunstetter Tyson J, Zwart Sara R, Brandt Keith, Brown David M, Clemett Simon J, Douglas Grace L et al.

A severe SANS case in an astronaut with genetic predispositions showed significant ocular changes and improvement, possibly linked to B-vitamin supplementation or reduced CO2, highlighting potential interventions for spaceflight-induced vision issues.

Fan Janet, Davila Pamela, Laylani Noor, Lee Andrew G, Frishberg Benjamin

A migraine with aura patient developed persistent vision loss due to a rare migrainous infarction in the occipital lobe, highlighting this serious complication's need for consideration in such cases.

Waisberg Ethan, Ong Joshua, Masalkhi Mouayad, Lee Andrew G, Berdahl John

Liu Katy C, Fleischman David, Lee Andrew G, Killer Hanspeter E, Chen John J, Bhatti M Tariq

CSF dynamics and the translaminar pressure gradient are key to optic disk health. Alterations in this gradient, driven by ICP and IOP, cause disk edema or cupping, impacting conditions like glaucoma and papilledema.

Lee Andrew G, Mader Thomas H, Gibson C Robert, Brunstetter Tyson J, Tarver William J

Long-duration spaceflight causes SANS, including optic disc edema and globe flattening. Understanding SANS is crucial for protecting astronauts' vision during future space missions.

Lee Andrew G

Chamberlain Paul D, Sadaka Ama, Berry Shauna, Lee Andrew G

Ethambutol optic neuropathy affects ~1% of patients, causing potentially irreversible blindness. Regular screening, including OCT, and timely drug discontinuation are crucial for prevention and management.

Lee Andrew G, Mader Thomas H, Gibson C Robert, Tarver William

Astronauts develop SANS, a neuro-ocular condition with optic disc edema, globe flattening, and vision changes, linked to spaceflight. Understanding SANS is crucial for future long-duration space missions.

Mader Thomas H, Gibson C Robert, Pass Anastas F, Kramer Larry A, Lee Andrew G, Fogarty Jennifer et al.

Long-duration spaceflight causes optic disc edema, globe flattening, choroidal folds, and hyperopic shifts in astronauts, likely due to fluid shifts, highlighting microgravity's impact on ocular health.

Alsuhaibani Adel H, Carter Keith D, Nerad Jeffrey A, Lee Andrew G

Unilateral optic nerve sheath fenestration significantly reduces papilledema in both operated and unoperated eyes in IIH, suggesting bilateral surgery may not always be needed for visual improvement.

Tagg Nathan T, Lee Andrew G, Syed Nasreen A, Golnik Karl C

Combined retinal artery and vein occlusion can signal metastatic cancer to the optic nerve sheath, highlighting the need for clinicians to consider optic nerve disorders as a cause of retinal vascular disease.

Hood Donald C, Anderson Susan, Rouleau Jacinthe, Wenick Adam S, Grover Larissa K, Behrens Myles M et al.

This study found a linear relationship between retinal nerve fiber loss and visual field sensitivity in ischemic optic neuropathy patients, similar to glaucoma. This model helps estimate residual nerve tissue, potentially identifying viable but dysfunctional axons.

Allen Richard C, Nerad Jeffrey A, Kattah Jorge C, Lee Andrew G

Optic nerve sheath fenestration successfully resolved optic nerve edema and improved vision in an osteopetrosis patient, suggesting it's a viable treatment when optic canals are open.

Lee Andrew G, Zimmerman M Bridget

This study found optic nerve head drusen causes slow visual field loss (1.6%/year), with older patients experiencing more severe loss. This highlights the need for ongoing monitoring.

Lee Andrew G, Chau Felix Y, Golnik Karl C, Kardon Randy H, Wall Michael

Studying unexplained optic atrophy, researchers found neuroimaging identified a compressive lesion in 20% of cases. This highlights the importance of neuroimaging for all patients with unexplained optic atrophy.

Lee Andrew G, Martin Coleman O

This study found visual symptoms, like field loss or cortical impairment, can be the primary sign of Alzheimer's disease, often preceding diagnosis. Ophthalmologists should consider vvAD in such cases.

Lee Andrew G

Lee Andrew G

Warner Russell B, Lee Andrew G

A patient developed LHON while using ephedra, alcohol, and tobacco. Ephedra likely exacerbated mitochondrial dysfunction, suggesting LHON patients should avoid such supplements due to potential additive toxicity.

Lee Andrew G, Golnik Karl, Kardon Randy, Wall Michael, Eggenberger Eric, Yedavally Sunita

This study found sleep apnea was common in men with idiopathic intracranial hypertension (IIH). Treating sleep apnea, often with CPAP, may improve IIH signs and symptoms in these men.