Murakami Yusuke

Fujiwara Kohta, Ueda Emi, Hata Jun, Nakano Satoko, Hashimoto Sawako, Nakamura Shun et al.

In a Japanese population, lower corneal hysteresis was significantly associated with higher glaucoma prevalence, especially for POAG and exfoliation glaucoma, suggesting its utility in understanding glaucoma etiology.

Tao Yan, Fukushima Masatoshi, Shimokawa Sakurako, Zhao Huanyu, Okita Ayako, Fujiwara Kohta et al.

This study found elevated ocular inflammatory molecules, especially IL-23, in RP patients, with correlations between ocular and systemic levels and an association with faster visual acuity loss.

Fujiwara Kohta, Yasuda Miho, Hata Jun, Nakano Satoko, Hashimoto Sawako, Ueda Emi et al.

This Japanese study found 7.6% glaucoma prevalence, identifying systemic factors like lower eGFR for POAG and diabetes for PACG/exfoliation glaucoma as crucial risk factors for prevention.

Murakami Yusuke, Koyanagi Yoshito, Fukushima Masatoshi, Yoshimura Marika, Fujiwara Kohta, Akiyama Masato et al.

This study found the common c.802-8_810del17insGC mutation in East Asian Bietti crystalline dystrophy patients doesn't cause more severe vision loss, suggesting its clinical impact isn't disproportionately harsh.

Fujiwara Kohta, Ikeda Yasuhiro, Murakami Yusuke, Tachibana Takashi, Funatsu Jun, Koyanagi Yoshito et al.

In RP patients, increased aqueous flare was linked to faster central visual field loss, suggesting it could be a useful marker for disease progression.

Ishikawa Keijiro, Kohno Ri-Ichiro, Mori Kenichiro, Murakami Yusuke, Nakao Shintaro, Akiyama Masato et al.

This study found significantly elevated periostin and tenascin-C in neovascular glaucoma, suggesting their role in disease development and potential as therapeutic targets for this severe condition.

Hisatomi Toshio, Tachibana Takashi, Notomi Shoji, Nakatake Shunji, Fujiwara Kohta, Murakami Yusuke et al.

Monkey studies showed that after ILM peeling, the retina remains incompletely repaired for years, with exposed nerve fibers and structural changes resembling clinical dissociated optic nerve layer or dimple signs.

Fujiwara Kohta, Ikeda Yasuhiro, Murakami Yusuke, Nakatake Shunji, Tachibana Takashi, Yoshida Noriko et al.

This study found elevated intraocular inflammation (aqueous flare) is associated with epiretinal membrane in retinitis pigmentosa, suggesting inflammation may cause this complication.

Yoshida Noriko, Ikeda Yasuhiro, Murakami Yusuke, Nakatake Shunji, Fujiwara Kota, Notomi Shoji et al.

This study found cataract surgery improved vision in about half of RP patients. Preoperative visual field (MD) and OCT ellipsoid zone status predict postoperative visual outcomes, guiding patient selection.

Yoshida Noriko, Ikeda Yasuhiro, Notomi Shoji, Ishikawa Keijiro, Murakami Yusuke, Hisatomi Toshio et al.

This study found sustained inflammation (vitreous cells, elevated cytokines) in retinitis pigmentosa patients. This suggests inflammation contributes to RP progression, opening avenues for anti-inflammatory treatments.

Ikeda Yasuhiro, Hisatomi Toshio, Yoshida Noriko, Notomi Shoji, Murakami Yusuke, Enaida Hiroshi et al.

Topical dorzolamide effectively reduced retinal thickness and improved macular sensitivity in patients with retinitis pigmentosa-associated cystoid macular edema, offering a promising treatment for this vision-threatening complication.

Yoshida Noriko, Hisatomi Toshio, Ikeda Yasuhiro, Kohno Ri-ichiro, Murakami Yusuke, Imaki Hiroyuki et al.

Intravitreal bevacizumab for neovascular glaucoma reduced inflammation, edema, and vascular congestion, plus caused endothelial cell degeneration in trabeculectomy specimens, suggesting its beneficial biological effects.

Suzuki Jun, Manola Akrivi, Murakami Yusuke, Morizane Yuki, Takeuchi Kimio, Kayama Maki et al.

AICAR significantly reduced inflammation in rat endotoxin-induced uveitis by suppressing inflammatory mediators and pathways. This suggests AICAR could be a novel therapeutic agent for ocular inflammation.