Nivison-Smith Lisa

Trinh Matt, Nguyen James, Lee Mary, Wang Jennifer, Tee Yoh Ghen, Nivison-Smith Lisa

iAMD shows faster, more sensitive reflectivity decreases (RNFL, GCL, EZ) than thickness changes, especially parafoveally. Reflectivity is a superior biomarker for early, dynamic retinal alterations in iAMD progression.

Trinh Matt, Borrelli Enrico, Reibaldi Michele, Foti Claudio, Nivison-Smith Lisa

Inner retinal reflectivity loss and mild RNFL thickening on OCT independently predict short-term iAMD to nAMD conversion. These novel biomarkers enhance risk stratification and monitoring for AMD patients.

Phu Jack, Khuu Sieu K, Nivison-Smith Lisa, Kalloniatis Michael

This review explored standard automated perimetry's issues in glaucoma/retinal diseases. It found optimizing parameters and reconciling subjective responses can improve defect detection and structure-function correlation, enhancing clinical care.

Trinh Matt, Kalloniatis Michael, Khuu Sieu K, Nivison-Smith Lisa

This review found early/intermediate AMD significantly reduces mesopic/scotopic retinal sensitivity, especially with MP-1/MAIA devices, providing clinically relevant measures for disease monitoring.

Trinh Matt, Kalloniatis Michael, Alonso-Caneiro David, Nivison-Smith Lisa

This study found intermediate AMD features like drusen, pigmentary changes, and reticular pseudodrusen cause distinct, often superior/central, retinal sensitivity loss patterns. This highlights that structural imaging alone underestimates functional visual impairment in iAMD.

Trinh Matt, Kalloniatis Michael, Alonso-Caneiro David, Nivison-Smith Lisa

High-density OCT revealed early/intermediate AMD causes widespread, unique thickness changes across all retinal layers, with poor interlayer correlation, highlighting the need for comprehensive retinal assessment.

Trinh Matt, Khou Vincent, Kalloniatis Michael, Nivison-Smith Lisa

OCT showed intermediate AMD eyes have central RPE-BM thickening but outer and inner retinal thinning, suggesting distinct anatomical changes. This helps target AMD diagnosis and monitoring.

Trinh Matt, Tong Janelle, Yoshioka Nayuta, Zangerl Barbara, Kalloniatis Michael, Nivison-Smith Lisa

Intermediate AMD eyes showed non-uniform macula ganglion cell layer changes, with more thickening than thinning, varying by location. This aids understanding and monitoring GCL pathologies.

Tong Janelle, Phu Jack, Khuu Sieu K, Yoshioka Nayuta, Choi Agnes Y, Nivison-Smith Lisa et al.

This study modeled age-related macular GCL changes, finding decline starts in the late 30s. Combining spatial clustering and age-correction improved visual field prediction, aiding early glaucoma detection.

Phu Jack, Khuu Sieu K, Nivison-Smith Lisa, Zangerl Barbara, Choi Agnes Yiu Jeung, Jones Bryan W et al.

This study found visual field sensitivity decline with age varies by stimulus size and location, creating unique patterns. These patterns could improve glaucoma diagnosis by guiding more precise comparisons of visual function.

Yoshioka Nayuta, Zangerl Barbara, Nivison-Smith Lisa, Khuu Sieu K, Jones Bryan W, Pfeiffer Rebecca L et al.

Pattern recognition identified age-related macular GCL thinning patterns in healthy eyes, with a segmented linear reduction. This provides a better framework for assessing GCL loss in glaucoma and other ocular diseases.