Trinh Matt

Trinh Matt, Nguyen James, Lee Mary, Wang Jennifer, Tee Yoh Ghen, Nivison-Smith Lisa

iAMD shows faster, more sensitive reflectivity decreases (RNFL, GCL, EZ) than thickness changes, especially parafoveally. Reflectivity is a superior biomarker for early, dynamic retinal alterations in iAMD progression.

Trinh Matt, Borrelli Enrico, Reibaldi Michele, Foti Claudio, Nivison-Smith Lisa

Inner retinal reflectivity loss and mild RNFL thickening on OCT independently predict short-term iAMD to nAMD conversion. These novel biomarkers enhance risk stratification and monitoring for AMD patients.

Trinh Matt, Kalloniatis Michael, Khuu Sieu K, Nivison-Smith Lisa

This review found early/intermediate AMD significantly reduces mesopic/scotopic retinal sensitivity, especially with MP-1/MAIA devices, providing clinically relevant measures for disease monitoring.

Trinh Matt, Kalloniatis Michael, Alonso-Caneiro David, Nivison-Smith Lisa

This study found intermediate AMD features like drusen, pigmentary changes, and reticular pseudodrusen cause distinct, often superior/central, retinal sensitivity loss patterns. This highlights that structural imaging alone underestimates functional visual impairment in iAMD.

Trinh Matt, Kalloniatis Michael, Alonso-Caneiro David, Nivison-Smith Lisa

High-density OCT revealed early/intermediate AMD causes widespread, unique thickness changes across all retinal layers, with poor interlayer correlation, highlighting the need for comprehensive retinal assessment.

Trinh Matt, Khou Vincent, Kalloniatis Michael, Nivison-Smith Lisa

OCT showed intermediate AMD eyes have central RPE-BM thickening but outer and inner retinal thinning, suggesting distinct anatomical changes. This helps target AMD diagnosis and monitoring.

Trinh Matt, Tong Janelle, Yoshioka Nayuta, Zangerl Barbara, Kalloniatis Michael, Nivison-Smith Lisa

Intermediate AMD eyes showed non-uniform macula ganglion cell layer changes, with more thickening than thinning, varying by location. This aids understanding and monitoring GCL pathologies.