Ogata Nahoko

Yoshikawa Tadanobu, Jimura Hironobu, Miyata Kimie, Obayashi Kenji, Saeki Keigo, Ogata Nahoko et al.

In glaucoma, reduced optic nerve head blood flow correlated with impaired intrinsically photosensitive retinal ganglion cell function, suggesting vascular compromise impacts these cells, potentially aiding early detection or monitoring.

Jimura Hironobu, Yoshikawa Tadanobu, Obayashi Kenji, Miyata Kimie, Saeki Keigo, Ogata Nahoko

Glaucoma patients with worse ipRGC function (lower PIPR) had significantly poorer subjective and objective sleep quality, especially those with severe glaucoma, highlighting a potential non-visual impact.

Yoshikawa Tadanobu, Obayashi Kenji, Miyata Kimie, Saeki Keigo, Ogata Nahoko

This study found that impaired ipRGC function, measured by pupil response, significantly correlates with both functional and structural glaucoma severity, suggesting its potential as a glaucoma biomarker.

Yoshikawa Tadanobu, Obayashi Kenji, Miyata Kimie, Saeki Keigo, Ogata Nahoko

This study found severe glaucoma damage is significantly linked to lower cognitive function, independent of age/vision, suggesting a need for cognitive assessment in advanced glaucoma.

Yoshikawa Tadanobu, Obayashi Kenji, Miyata Kimie, Saeki Keigo, Ogata Nahoko

This study found higher serum ADMA levels are significantly associated with more severe glaucoma, suggesting ADMA could be a biomarker or therapeutic target for the disease.

Yoshikawa Tadanobu, Obayashi Kenji, Miyata Kimie, Saeki Keigo, Ogata Nahoko

Glaucoma patients exhibited significantly higher nighttime blood pressure and a greater prevalence of non-dipping patterns. This suggests nocturnal BP dysregulation may be a glaucoma risk factor requiring further investigation.

Yoshikawa Tadanobu, Obayashi Kenji, Miyata Kimie, Ueda Tetsuo, Kurumatani Norio, Saeki Keigo et al.

This study found glaucoma's optic disc changes are significantly associated with higher depressive symptoms in the elderly, independent of daily light exposure, highlighting a direct link.

Yoshikawa Tadanobu, Yamanaka Chihiro, Kinoshita Takamasa, Morikawa Shohei, Ogata Nahoko

This study found vitrectomy effectively resolves macular retinoschisis in glaucoma patients with severe vision loss, while some untreated cases may resolve spontaneously without vision change.

Okamoto Masahiro, Matsuura Toyoaki, Ogata Nahoko

PRP for severe NPDR significantly reduced subfoveal choroidal thickness and blood flow, suggesting this mechanism contributes to PRP's therapeutic success.

Ogata Nahoko, Imaizumi Masahito, Miyashiro Miki, Arichi Miwa, Matsuoka Masato, Ando Akira et al.

Highly myopic eyes, especially with chorioretinal atrophy, showed significantly lower aqueous PEDF levels. This suggests PEDF reduction may contribute to myopic degeneration, potentially guiding future therapeutic strategies.

Ogata Nahoko, Matsuoka Masato, Imaizumi Masahito, Arichi Miwa, Matsumura Miyo

This study found significantly lower PEDF levels in the aqueous humor of eyes with retinitis pigmentosa and advanced glaucoma, suggesting PEDF deficiency may contribute to neuroretinal degeneration.

Ogata Nahoko, Matsuoka Masato, Imaizumi Masahito, Arichi Miwa, Matsumura Miyo

Aqueous humor PEDF levels decrease with age, a finding potentially relevant for understanding age-related eye diseases, especially those involving angiogenesis.

Ogata Nahoko, Wada Mitsumasa, Otsuji Tsuyoshi, Jo Nobuo, Tombran-Tink Joyce, Matsumura Miyo

This study found PEDF is expressed in normal rat eyes and choroidal neovascularization (CNV) lesions. This suggests PEDF may modulate CNV, offering a potential therapeutic target.