Petzold Axel

Neo Yan Ning, Martinez-Alvarez Lidia, Davagnanam Indran, Girafa Gabriela, Bremner Fion, Braithwaite Tasanee et al.

Post-vaccination optic neuritis shows older onset, higher bilaterality, and excellent visual recovery. Early corticosteroids are crucial for neuroprotection and favorable outcomes, despite retinal atrophy. Autoantibody status is important for long-term management.

Ribeiro Reis Ana Paula, Ioannidou Estelle, Stuart Kelsey V, Wagner Siegfried K, Foster Paul J, Khawaja Anthony P et al.

This review found limited, inconsistent data on how women's hormonal cycles affect eye structures, though choroidal thinning was noted during the luteal phase. More research is needed to understand sex differences in eye diseases.

Laviers Heidi, Petzold Axel, Braithwaite Tasanee

This UK review highlights that prompt identification of atypical optic neuritis causes (beyond MS) is crucial for tailored, urgent corticosteroid treatment to prevent irreversible vision loss.

Kleerekooper Iris, Wagner Siegfried K, Trip S Anand, Plant Gordon T, Petzold Axel, Keane Pearse A et al.

A new macular OCT ratio (mNTR) effectively differentiates glaucoma from chiasmal compression, offering a clinically useful tool for early diagnosis and distinguishing these conditions.

Martin-Gutierrez M Pilar, Petzold Axel, Saihan Zubin

This review highlights that various conditions mimic anterior ischemic optic neuropathy (NAION). Differentiating these look-alikes through clinical history and multimodal imaging is crucial to avoid misdiagnosis and unnecessary procedures.

Bennett Jeffrey L, Costello Fiona, Chen John J, Petzold Axel, Biousse Valérie, Newman Nancy J et al.

This review highlights that optic neuritis subtypes, like those linked to MS or MOGAD, have distinct prognoses. Early, accurate diagnosis guides tailored treatments, improving visual outcomes and preventing severe atrophy.

Nij Bijvank Jenny, Maillette de Buy Wenniger Lucas, de Graaf Pim, Petzold Axel

This review explores retinotopy using OCT and MRI, revealing how visual system neurodegeneration patterns, guided by anatomy, offer new insights for diagnosing and monitoring neuroprotective strategies.

Maloca Peter M, de Carvalho Emanuel R, Hasler Pascal W, Balaskas Konstantinos, Inglin Nadja, Petzold Axel et al.

This study used 3D OCT to measure pupillary function, finding significantly reduced pupillary contractility (PEF) in pseudoexfoliation glaucoma and NAION, offering a potential new monitoring tool.

Huemer Josef, Khalid Hagar, Ferraz Daniel, Faes Livia, Korot Edward, Jurkute Neringa et al.

This study found that after diabetic optic disc swelling resolves, both diabetic papillopathy and NAION show pRNFL and mGCL thinning, but preserved mINL. This atrophy correlates with poor vision, suggesting prognostic value regardless of specific diagnosis.

Minakaran Neda, de Carvalho Emanuel R, Petzold Axel, Wong Sui H

OCT non-invasively characterizes optic nerve and macular layers, improving assessment and management of neuro-ophthalmic conditions like optic neuropathies.

Petzold Axel, Balcer Laura J, Calabresi Peter A, Costello Fiona, Frohman Teresa C, Frohman Elliot M et al.

This meta-analysis found peripapillary RNFL and macular GCIPL thinning are robust biomarkers for MS neurodegeneration, recommending their use for diagnosis, monitoring, and research.

Balk Lisanne J, Petzold Axel

Balk Lisanne J, Sonder Judith M, Strijbis Eva M M, Twisk Jos W R, Killestein Joep, Uitdehaag Bernard M J et al.

This study found runners' RNFL thickness and macular volume significantly increased after exercise/rehydration, a physiological variation relevant for longitudinal neurodegenerative disease monitoring.