Proudlock Frank A

Sheth Viral, McLean Rebecca J, Tu Zhanhan, Ather Sarim, Gottlob Irene, Proudlock Frank A

This study found significant visual field deficits in albinism and infantile nystagmus, with albinism patients having considerably worse fields. Clinically, these findings highlight the need for cautious interpretation of perimetry in these conditions.

Nuijts Myrthe A, Stegeman Inge, Porro Giorgio L, Bennebroek Carlien A M, van Seeters Tom, Proudlock Frank A et al.

This study found OCT's RNFL thickness could detect abnormal vision in children with new brain tumors in 70% of cases. High negative predictive values suggest normal OCT indicates normal visual function.

Pilat Anastasia V, Proudlock Frank A, Kumar Periyasamy, Gottlob Irene

This study found that patients with optic nerve head drusen experienced significant optic nerve and macular thinning within just one year, highlighting rapid structural progression relevant for monitoring.

Rufai Sohaib R, Bowman Richard, Bunce Catey, Panteli Vasiliki, McLean Rebecca J, Teli Seema et al.

Handheld OCT is feasible and repeatable in children with craniosynostosis, offering a valuable tool for monitoring optic nerve health and detecting intracranial hypertension.

Edawaji Budor S A, Gottlob Irene, Proudlock Frank A

This study mapped anterior chamber development in children, finding rapid growth until 18 months, maturity by age 5, and sex differences. These measurements can aid understanding of pediatric anterior segment diseases.

Shah Sonal D, Haq Adnaan, Toufeeq Shafak, Tu Zhanhan, Edawaji Budor, Abbott Joseph et al.

Hand-held OCT can reliably measure retinal nerve fiber layer thickness in awake children, proving feasible for glaucoma assessment, with optimal imaging at 6° from the optic nerve.

Pilat Anastasia V, Proudlock Frank A, Shah Sonal, Sheth Viral, Purohit Ravi, Abbot Joseph et al.

Handheld OCT non-invasively visualized key anterior segment abnormalities in congenital glaucoma, like corneal changes and iris flattening, without sedation, offering a valuable tool for diagnosis and surgical planning.

Patel Aarti, Purohit Ravi, Lee Helena, Sheth Viral, Maconachie Gail, Papageorgiou Eleni et al.

Handheld SD-OCT successfully imaged pediatric ONH development. Key finding: Disc/cup diameters increase with age, while peripapillary RNFL initially decreases then slowly increases, providing normative data for clinical use.

Pilat Anastasia, McLean Rebecca J, Proudlock Frank A, Maconachie Gail D E, Sheth Viral, Rajabally Yusuf A et al.

This study found Parkinson's patients have significant optic nerve fiber thinning and foveal remodeling, including retinal thinning and OPL thickening. These changes, correlating with disease severity, could be valuable Parkinson's biomarkers.

Lee Helena, Proudlock Frank A, Gottlob Irene

Handheld OCT offers novel insights into pediatric retinal and optic nerve diseases, aiding diagnosis, monitoring, and potentially guiding earlier, more effective treatments for conditions like ROP, nystagmus, and glaucoma.

Pilat Anastasia, Sibley Daniel, McLean Rebecca J, Proudlock Frank A, Gottlob Irene

SD OCT revealed ONH patients have smaller optic discs and retinal thinning (RNFL, GCL), often with foveal hypoplasia. These OCT parameters offer high sensitivity/specificity for ONH diagnosis.

Pilat Anastasia V, Proudlock Frank A, Kumar Periyasamy, Lee Helena, Papageorgiou Eleni, Gottlob Irene

This study used OCT to find distinct macular layer changes in optic nerve head drusen and optic disc edema, suggesting these specific patterns aid diagnosis and understanding of each condition.