Gottlob Irene

Papageorgiou Eleni, Toumasis Panagiotis N, Lazari Katerina, Androudi Sofia, Gottlob Irene

OCT is a vital non-invasive tool in pediatric ophthalmology, providing structural insights into ocular development and guiding diagnosis and management across diverse eye diseases, even in uncooperative children.

Rufai Sohaib R, Roche Dermot, Shenoy Riddhi, Marmoy Oliver R, Panteli Vasiliki, Thomson Dorothy A et al.

This study found handheld and table-mounted OCT are feasible and comparable for monitoring optic nerves in children with craniosynostosis, enabling data pooling for enhanced care and research.

Rufai Sohaib R, Thomas Mervyn G, Marmoy Oliver R, Panteli Vasiliki, Thompson Dorothy A, Bunce Catey et al.

This study found children with craniosynostosis have distinct optic nerve head morphology, especially in FGFR1/2 syndromes, which could improve ophthalmological monitoring and surgical decisions.

Sheth Viral, McLean Rebecca J, Tu Zhanhan, Ather Sarim, Gottlob Irene, Proudlock Frank A

This study found significant visual field deficits in albinism and infantile nystagmus, with albinism patients having considerably worse fields. Clinically, these findings highlight the need for cautious interpretation of perimetry in these conditions.

Molz Barbara, Herbik Anne, Baseler Heidi A, de Best Peter, Raz Noa, Gouws Andre et al.

Studying achromatopsia, researchers found no significant remapping of the central visual cortex. This suggests less brain plasticity than thought, which is important for future gene therapies.

Pilat Anastasia V, Proudlock Frank A, Kumar Periyasamy, Gottlob Irene

This study found that patients with optic nerve head drusen experienced significant optic nerve and macular thinning within just one year, highlighting rapid structural progression relevant for monitoring.

Rufai Sohaib R, Bowman Richard, Bunce Catey, Panteli Vasiliki, McLean Rebecca J, Teli Seema et al.

Handheld OCT is feasible and repeatable in children with craniosynostosis, offering a valuable tool for monitoring optic nerve health and detecting intracranial hypertension.

Edawaji Budor S A, Gottlob Irene, Proudlock Frank A

This study mapped anterior chamber development in children, finding rapid growth until 18 months, maturity by age 5, and sex differences. These measurements can aid understanding of pediatric anterior segment diseases.

Thomas Mervyn G, Papageorgiou Eleni, Kuht Helen J, Gottlob Irene

This study examined normal and abnormal foveal development, finding foveal morphology and grading using OCT correlate strongly with visual acuity, aiding diagnosis and prognosis in children with foveal hypoplasia.

Shah Sonal D, Haq Adnaan, Toufeeq Shafak, Tu Zhanhan, Edawaji Budor, Abbott Joseph et al.

Hand-held OCT can reliably measure retinal nerve fiber layer thickness in awake children, proving feasible for glaucoma assessment, with optimal imaging at 6° from the optic nerve.

Pilat Anastasia V, Proudlock Frank A, Shah Sonal, Sheth Viral, Purohit Ravi, Abbot Joseph et al.

Handheld OCT non-invasively visualized key anterior segment abnormalities in congenital glaucoma, like corneal changes and iris flattening, without sedation, offering a valuable tool for diagnosis and surgical planning.

Patel Aarti, Purohit Ravi, Lee Helena, Sheth Viral, Maconachie Gail, Papageorgiou Eleni et al.

Handheld SD-OCT successfully imaged pediatric ONH development. Key finding: Disc/cup diameters increase with age, while peripapillary RNFL initially decreases then slowly increases, providing normative data for clinical use.

Pilat Anastasia, McLean Rebecca J, Proudlock Frank A, Maconachie Gail D E, Sheth Viral, Rajabally Yusuf A et al.

This study found Parkinson's patients have significant optic nerve fiber thinning and foveal remodeling, including retinal thinning and OPL thickening. These changes, correlating with disease severity, could be valuable Parkinson's biomarkers.

Lee Helena, Proudlock Frank A, Gottlob Irene

Handheld OCT offers novel insights into pediatric retinal and optic nerve diseases, aiding diagnosis, monitoring, and potentially guiding earlier, more effective treatments for conditions like ROP, nystagmus, and glaucoma.

Mohammad Sarim, Gottlob Irene, Sheth Viral, Pilat Anastasia, Lee Helena, Pollheimer Ellen et al.

Albinism causes distinct optic nerve head maldevelopment, with smaller optic cups, larger rims, and thinner retinal nerve fiber layers, crucial for differentiating from glaucoma.

Pilat Anastasia, Sibley Daniel, McLean Rebecca J, Proudlock Frank A, Gottlob Irene

SD OCT revealed ONH patients have smaller optic discs and retinal thinning (RNFL, GCL), often with foveal hypoplasia. These OCT parameters offer high sensitivity/specificity for ONH diagnosis.

Pilat Anastasia V, Proudlock Frank A, Kumar Periyasamy, Lee Helena, Papageorgiou Eleni, Gottlob Irene

This study used OCT to find distinct macular layer changes in optic nerve head drusen and optic disc edema, suggesting these specific patterns aid diagnosis and understanding of each condition.

Lee Helena, Proudlock Frank, Gottlob Irene

Handheld OCT reliably measures foveal thickness in young children, even with nystagmus, showing excellent reproducibility. This validates its future use for diagnosing and monitoring pediatric eye diseases.

Proudlock Frank Antony, Khanna Aman, Gottlob Irene

This study found visual "filling-in" takes longer along horizontal meridians, correlating with contrast sensitivity and cone density. This anisotropy helps understand visual processing and potential glaucoma-related visual field changes.