Quillen Sarah E

Quillen Sarah E, Kimball Elizabeth C, Ritter-Gordy Kelsey A, Du Liya, Yuan Zhuochen, Pease Mary E et al.

Topical ripasudil reduced retinal ganglion cell loss in mouse glaucoma and optic nerve injury by suppressing ROCK signaling. This suggests a neuroprotective mechanism for RGCs and astrocytes.

Korneva Arina, Kimball Elizabeth C, Johnson Thomas V, Quillen Sarah E, Pease Mary E, Quigley Harry A et al.

This study found glaucoma (high IOP) altered mouse astrocytic lamina mechanics, but optic nerve crush (axon damage) did not, suggesting IOP-induced changes, not just axon injury, affect lamina biomechanics.