Kimball Elizabeth C

Quillen Sarah E, Kimball Elizabeth C, Ritter-Gordy Kelsey A, Du Liya, Yuan Zhuochen, Pease Mary E et al.

Topical ripasudil reduced retinal ganglion cell loss in mouse glaucoma and optic nerve injury by suppressing ROCK signaling. This suggests a neuroprotective mechanism for RGCs and astrocytes.

Korneva Arina, Kimball Elizabeth C, Johnson Thomas V, Quillen Sarah E, Pease Mary E, Quigley Harry A et al.

This study found glaucoma (high IOP) altered mouse astrocytic lamina mechanics, but optic nerve crush (axon damage) did not, suggesting IOP-induced changes, not just axon injury, affect lamina biomechanics.

Ling Yik Tung Tracy, Pease Mary E, Jefferys Joan L, Kimball Elizabeth C, Quigley Harry A, Nguyen Thao D

Mouse optic nerve astrocytes showed significant structural changes, especially in unmyelinated regions, after 3 days of ocular hypertension, revealing early mechanotransduction relevant to glaucoma.

Schaub Julie A, Kimball Elizabeth C, Steinhart Matthew R, Nguyen Cathy, Pease Mary E, Oglesby Ericka N et al.

Mouse glaucoma showed selective RGC axon loss, predominantly in superior and temporal optic nerve regions, mirroring human glaucoma patterns, suggesting strain-specific damage responses.

Nguyen Cathy, Midgett Dan, Kimball Elizabeth C, Steinhart Matthew R, Nguyen Thao D, Pease Mary E et al.

This study measured mouse optic nerve head and peripapillary sclera deformation under pressure. It found regional differences in how these tissues respond to acute and chronic IOP changes, providing insights into glaucoma's mechanical effects.