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Secretion of matrix metalloproteinase-3 by co-cultured pigmented and non-pigmented human trabecular meshwork cells following selective laser trabeculoplasty.
Lee James Y J, Kagan Dov B, Roumeliotis Grayson, Liu Hong, Hutnik Cindy M L
Clin Exp OphthalmolDec 201520 citationsBasic Science
SLT induces MMP-3 secretion and cell death in pigmented trabecular meshwork cells, but not non-pigmented ones. This highlights pigmentation's role in SLT's mechanism, influencing its efficacy.