Liu Hong

Teplitsky Jack E, Vinokurtseva Anastasiya, Armstrong James J, Denstedt James, Liu Hong, Hutnik Cindy M L

This study found the TGFβ1 inhibitor SB-431542 effectively reduced scarring in human eye cells, similar to Mitomycin C, but with significantly less toxicity, suggesting a safer antifibrotic for glaucoma surgery.

Tellios Nikoleta, Feng Mary, Chen Nancy, Liu Hong, Tellios Vasiliki, Wang Mary et al.

Mechanical stretch on trabecular meshwork cells increased Cx43 expression and communication, alongside cell injury, potentially explaining TM dysfunction in glaucoma.

Wang Wan Wendy, Watson Kelsey A, Dixon S Jeffrey, Liu Hong, Rizkalla Amin S, Hutnik Cindy Ml

Studying MIGS metals, researchers found nitinol negatively impacted human trabecular meshwork cell viability and spreading more than titanium, highlighting material choice's importance for surgical success.

Lee James Y J, Kagan Dov B, Roumeliotis Grayson, Liu Hong, Hutnik Cindy M L

SLT induces MMP-3 secretion and cell death in pigmented trabecular meshwork cells, but not non-pigmented ones. This highlights pigmentation's role in SLT's mechanism, influencing its efficacy.

Chang Caitlin, Zhang Angela Q, Kagan Dov B, Liu Hong, Hutnik Cindy M L

This study found benzalkonium chloride (BAK) harms human trabecular meshwork cells, reducing viability and increasing apoptosis. Preservative-free tafluprost was safe and protected these cells from BAK toxicity, highlighting benefits of preservative-free glaucoma drops.

Yuen Darana, Gonder John, Proulx Alain, Liu Hong, Hutnik Cindy

This study compared intraocular dye toxicity on retinal cells, finding ICG safest overall, while other dyes showed toxicity at higher concentrations/longer exposures, guiding safer surgical dye selection.