Hutnik Cindy M L

Kanjee Raageen, Popovic Marko M, Salimi Ali, Hutnik Cindy M L, Ahmed Iqbal Ike K, Saheb Hady

This study found prophylactic medications effectively reduce immediate post-cataract surgery IOP spikes, with intracameral cholinergics and FCCB formulations being most effective.

Teplitsky Jack E, Vinokurtseva Anastasiya, Armstrong James J, Denstedt James, Liu Hong, Hutnik Cindy M L

This study found the TGFβ1 inhibitor SB-431542 effectively reduced scarring in human eye cells, similar to Mitomycin C, but with significantly less toxicity, suggesting a safer antifibrotic for glaucoma surgery.

Michaelov Evan, Armstrong James J, Nguyen Mary, Instrum Bridget, Lam Tracey, Denstedt James et al.

Most glaucoma guidelines are high quality but lack specific, up-to-date recommendations for microinvasive glaucoma surgery (MIGS), making them suboptimal for guiding clinical decisions and policy.

Armstrong James J, Wasiuta Tomas, Kiatos Efstathia, Malvankar-Mehta Monali, Hutnik Cindy M L

Cataract surgery (phacoemulsification) in glaucoma patients significantly lowers intraocular pressure and reduces medication use for at least 3 years, offering a beneficial standalone treatment.

Iordanous Yiannis, Hutnik Cindy M L, Malvankar-Mehta Monali S

Lee James Y J, Kagan Dov B, Roumeliotis Grayson, Liu Hong, Hutnik Cindy M L

SLT induces MMP-3 secretion and cell death in pigmented trabecular meshwork cells, but not non-pigmented ones. This highlights pigmentation's role in SLT's mechanism, influencing its efficacy.

Kent Shefalee S, Hutnik Cindy M L, Birt Catherine M, Damji Karim F, Harasymowycz Paul, Si Francie et al.

This study found SLT and ALT are equally effective at lowering IOP in pseudoexfoliation patients, suggesting both are viable initial treatment options.

Chang Caitlin, Zhang Angela Q, Kagan Dov B, Liu Hong, Hutnik Cindy M L

This study found benzalkonium chloride (BAK) harms human trabecular meshwork cells, reducing viability and increasing apoptosis. Preservative-free tafluprost was safe and protected these cells from BAK toxicity, highlighting benefits of preservative-free glaucoma drops.

Martow Evan, Hutnik Cindy M L, Mao Alexander

This study found pre-SLT eye pressure, not medication class, is the only predictor of SLT success, with higher initial pressure leading to better outcomes.

Tsui Edmund, Hill Kathleen A, Laliberte Alex M, Paluzzi Daniel, Kisilevsky Ilia, Shao Qing et al.

Studying ODDD mice, researchers found GJA1 mutations cause diverse ocular defects, including altered Cx43, low IOP, and structural changes, providing insights into human glaucoma mechanisms.

McIlraith Ian, Strasfeld Maurice, Colev George, Hutnik Cindy M L

This study found selective laser trabeculoplasty (SLT) is as effective as latanoprost for initial open-angle glaucoma treatment, supporting its use as a first-line therapy.