Voorhees Andrew P

Voorhees Andrew P, Hua Yi, Brazile Bryn L, Wang Bingrui, Waxman Susannah, Schuman Joel S et al.

This study found that missing lamina cribrosa tissue (defects) can *reduce* IOP-induced neural tissue strain, challenging the idea that defects are always detrimental. Partial tissue loss was biomechanically worse than complete loss.

Brazile Bryn L, Yang Bin, Waxman Susannah, Lam Po, Voorhees Andrew P, Hua Yi et al.

Pig eye studies showed lamina cribrosa capillaries straighten as IOP increases, suggesting tortuosity provides slack against damage. Low tortuosity might be a glaucoma risk factor.

Tran Huong, Wallace Jacob, Zhu Ziyi, Lucy Katie A, Voorhees Andrew P, Schmitt Samantha E et al.

Exsanguination improved optic nerve head lamina visibility and altered its morphology in primates. This suggests blood pressure influences ONH structure, impacting glaucoma research and imaging interpretation.

Hua Yi, Voorhees Andrew P, Sigal Ian A

This study modeled optic nerve head biomechanics, finding IOP and CSFP are top influential factors, but affect the ONH differently. CSFP strongly impacts peripapillary scleral rotation, suggesting translaminar pressure difference isn't ideal for predicting glaucoma.

Jan Ning-Jiun, Gomez Celeste, Moed Saundria, Voorhees Andrew P, Schuman Joel S, Bilonick Richard A et al.

This study found the optic nerve's lamina cribrosa has small, uniform collagen crimp, unlike the adjacent sclera. This microstructural difference likely protects neural tissue by minimizing deformation and stress, crucial for glaucoma understanding.