Zhang Shenghai

Zhao Yingke, Wu Jiawen, Li Chenchen, Cheng Yun, Li Qian, Wu Jianing et al.

136 proteins linked to glaucoma, with 4 causal (LTBP2, NRP2, TNFSF13, HAVCR1) detectable 12-15 years pre-diagnosis. This offers early risk stratification, targeted screening, and therapeutic targets for glaucoma.

Yuan Nini, Li Mengwei, Chen Xiaoxiao, Lu Yiliang, Fang Yuan, Gong Hongliang et al.

Acute IOP elevation (≥50 mmHg) in cats suppressed cortical motion processing, particularly fine discrimination in central vision. This suggests acute glaucoma impacts specific visual pathways, explaining immediate visual deficits.

Chen Junyi, Huang Haili, Zhang Shenghai, Chen Xueli, Sun Xinghuai

Travoprost expanded Schlemm's canal and lowered intraocular pressure in healthy eyes, suggesting it enhances outflow by widening this drainage structure.

Wu Jihong, Zhang Shenghai, Sun Xinghuai

This study found that Sonic Hedgehog (Shh) is upregulated and protects retinal ganglion cells in a rat glaucoma model, suggesting it's a potential neuroprotective therapy.