Chen Junyi

Qiao Yunsheng, Tan Chen, Lai Junyi, He Jiangnan, Zhu Jianfeng, Zou Haidong et al.

This study found Chinese glaucoma patients' quality of life is primarily driven by disease severity (visual acuity, field defects, IOP). Clinically, managing these factors is key to improving patient well-being.

Qiao Yunsheng, Sun Zhongmou, Tan Chen, Lai Junyi, Sun Xinghuai, Chen Junyi

AAV-DJ.COMP-ANG1 gene therapy lowered mouse eye pressure by remodeling the trabecular outflow pathway, enlarging Schlemm's canal and improving drainage. This suggests a novel glaucoma treatment approach.

Gao Feng, Wang Jiajian, Chen Junyi, Wang Xiaolei, Chen Yuhong, Sun Xinghuai

Gao Feng, Wang Jiajian, Chen Junyi, Wang Xiaolei, Chen Yuhong, Sun Xinghuai

This study found primary ACG, uveitis, and anterior segment dysgenesis are top causes of angle-closure glaucoma in young Chinese patients. Early, comprehensive examination is crucial for timely diagnosis and treatment.

Xuan Yi, Zhang Youjia, Zong Yuan, Wang Min, Li Lei, Ye Xiaofeng et al.

This study of Chinese vitelliform macular dystrophy patients found specific genetic mutations, and importantly, that BEST1-related cases had varying ocular biometrics, with some showing increased risk for angle-closure glaucoma.

Li Mengwei, Chen Yuhong, Jiang Zhenying, Chen Xiaoxiao, Chen Junyi, Sun Xinghuai

This study found primary angle closure with longer axial length is rare, predominantly male, and characterized by flatter corneas and smaller relative anterior segment dimensions, indicating diverse angle closure mechanisms.

Sun Xinghuai, Dai Yi, Chen Yuhong, Yu Dao-Yi, Cringle Stephen J, Chen Junyi et al.

This review highlights PACG's multi-mechanism pathogenesis beyond pupillary block, influenced by genetics. Effective treatments exist, but better early identification and novel therapies are needed for prevention and improved prognosis.

Li Mengwei, Kong Xiangmei, Zhu Wenqing, Chen Yuhong, Chen Junyi, Sun Xinghuai

Hong Jiaxu, Chen Junyi, Yang Yujing, Wei Anji, Kong Xiangmei, Yu Xiaobo et al.

Trabeculectomy significantly widens the anterior chamber angle in PACG, with this widening directly related to the reduction in intraocular pressure.

Yang Jin, Fan Qi, Chen Junyi, Wang Anjian, Cai Lei, Sheng Hui et al.

This study found that lens removal with IOL implantation effectively lowered intraocular pressure and improved vision in spherophakia patients with secondary glaucoma, regardless of zonular integrity.

Hong Jiaxu, Xu Jianjiang, Wei Anji, Wen Wen, Chen Junyi, Yu Xibao et al.

SD-OCT showed primary open-angle glaucoma patients have a smaller Schlemm's canal area, correlating with higher intraocular pressure. This suggests SC morphology impacts glaucoma, aiding future diagnostic/treatment strategies.

Chen Junyi, Huang Haili, Zhang Shenghai, Chen Xueli, Sun Xinghuai

Travoprost expanded Schlemm's canal and lowered intraocular pressure in healthy eyes, suggesting it enhances outflow by widening this drainage structure.

Huang Haili, Jonas Jost B, Dai Yi, Hong Jiaxu, Wang Min, Chen Junyi et al.

This study found that in advanced glaucoma, a central visual field island is associated with a more temporally located central retinal vessel trunk, suggesting CRVT position may influence visual field loss patterns.