Zhong Fuqiang

Lu Yuankai, Hua Yi, Wang Bingrui, Tian Qi, Zhong Fuqiang, Theophanous Andrew et al.

This study found that elevated IOP distorts the lamina cribrosa, significantly reducing its oxygenation and causing hypoxia. This suggests IOP-induced distortions contribute to glaucomatous nerve damage.

Bansal Manik, Wang Bingrui, Waxman Susannah, Zhong Fuqiang, Hua Yi, Lu Yuankai et al.

This study developed an axon-centric method to analyze IOP-induced mechanical insult. It found axons experience distinct, orientation-specific compression/stretch in different optic nerve head regions, unlike tissue-level strains, offering new insights into glaucoma damage.

Lu Yuankai, Hua Yi, Wang Bingrui, Zhong Fuqiang, Theophanous Andrew, Tahir Shaharoz et al.

This study simulated lamina cribrosa vessel collapse under high eye pressure. It found blood flow was sensitive to distributed collapse, while oxygenation was robust to it but vulnerable to clustered collapse.