Hadoux Xavier

Improvement in inner retinal function in glaucoma with nicotinamide (vitamin B3) supplementation: A crossover randomized clinical trial.

Nicotinamide supplementation can improve inner retinal function in glaucoma. Further studies underway to elucidate the effects of long-term nicotinamide supplementation.

A Comparison of the RETeval Sensor Strip and DTL Electrode for Recording the Photopic Negative Response.

Sensor strip electrodes are a viable alternative for recording reproducible PhNRs, especially when values are normalized to the b-wave.

Baseline Detrending for the Photopic Negative Response.

Baseline detrending can improve the PhNR repeatability without compromising its clinical use in glaucoma. Further studies exploring more complex processing methods are encouraged.

Systematic Underestimation of Visual Sensitivity Loss on Microperimetry: Implications for Testing Protocols in Clinical Trials.

The 4-2 staircase strategy conventionally used on microperimetry testing systematically underestimates visual sensitivity loss on the first test.

Short-Term Changes in the Photopic Negative Response Following Intraocular Pressure Lowering in Glaucoma.

The optimized protocol for measuring the PhNR detected short-term improvements in a proportion of participants following IOP reduction, although the majority showed no change.

Optimizing a Portable ERG Device for Glaucoma Clinic: The Effect of Interstimulus Frequency on the Photopic Negative Response.

An interstimulus frequency of 2 Hz was optimal for recording the PhNR, creating a good balance between testing time and signal quality.

High-Resolution Microperimetry for Detecting Glaucomatous Damage: A Prospective Evaluation of Performance.

High-resolution microperimetry enabled improved performance for detecting glaucomatous damage compared to SAP, highlighting the potential value of fundus-tracking and higher-resolution sampling for the detection of glaucomatous visual field loss.

Enhanced Detection of Glaucoma Progression Using Widefield Swept-Source OCT.

Qualitative evaluation of widefield OCT scans showed an enhanced detection rate for structural progression than cpRNFLT measurements in glaucoma eyes.

Photopic Negative Response Obtained Using a Handheld Electroretinogram Device: Determining the Optimal Measure and Repeatability.

The PhNR/B ratio was the measure that minimized variability, and its measurements using a novel handheld ERG system with self-adhering skin electrodes and the protocols described in this study were comparable under different testing conditions…

Test-Retest Variability of Fundus-Tracked Perimetry at the Peripapillary Region in Open Angle Glaucoma.

On a pointwise basis, the test-retest variability of visual sensitivity in glaucoma is not just related to its measured level, but also its local gradient when using fundus-tracked perimetry.

Measuring the Photopic Negative Response: Viability of Skin Electrodes and Variability Across Disease Severities in Glaucoma.

Skin electrodes are a viable alternative to conjunctival electrodes when measuring the PhNR in open angle glaucoma, and increasing the number of sweeps substantially reduced its intrinsic variability; the extent of variability was also lower…