Myers Jonathan S

An Artificial Intelligence Approach to Detect Visual Field Progression in Glaucoma Based on Spatial Pattern Analysis.

The archetype method can inform clinicians of VF progression patterns.

Philadelphia Telemedicine Glaucoma Detection and Follow-up Study: Methods and Screening Results.

An integrated telemedicine screening intervention in primary care offices and Federally Qualified Health Centers detected high rate of suspicious optic nerves, ocular hypertension, and retinal pathology.

Artificial Intelligence Classification of Central Visual Field Patterns in Glaucoma.

We quantified central VF patterns in glaucoma, which were used to improve the prediction of central VF worsening compared with using only global indices.

Characterization of Central Visual Field Loss in End-stage Glaucoma by Unsupervised Artificial Intelligence.

In this study, central VF loss in end-stage glaucoma was found to exhibit characteristic patterns that might be associated with different subtypes.

Implantation of two second-generation trabecular micro-bypass stents and topical travoprost in open-angle glaucoma not controlled on two preoperative medications: 18-month follow-up.

In open-angle glaucoma eyes on two preoperative medications, treatment with two second-generation trabecular stents and one postoperative prostaglandin resulted in mean intraocular pressure ≤ 13 mmHg with reduction of one medication, with favourable safety.

Reversal of Glaucoma Hemifield Test Results and Visual Field Features in Glaucoma.

Using VF features may predict the GHT results reversal to WNL after 2 consecutive ONL results.

Preliminary Report on a Novel Virtual Reality Perimeter Compared With Standard Automated Perimetry.

There was an excellent correlation between the VisuALL and the Standard Automated Perimetry in normal and glaucoma patients and VisuALL showing high diagnostic performance.

Evolution of optic nerve photography for glaucoma screening: a review.

Newer technology has made optic nerve photography simpler, cheaper and more portable creating opportunities for broader utilization in screening in underserved populations by non-physicians.

Pooled Efficacy and Safety Profile of Netarsudil Ophthalmic Solution 0.02% in Patients With Open-angle Glaucoma or Ocular Hypertension.

Once-daily netarsudil resulted in IOP lowering that was noninferior to twice-daily timolol, with tolerable ocular AEs that were generally mild and self-resolving.

Agreement and Predictors of Discordance of 6 Visual Field Progression Algorithms.

This extremely large comparative series demonstrated that existing algorithms have limited agreement and that agreement varies with clinical parameters, including institution.

Monitoring Glaucomatous Functional Loss Using an Artificial Intelligence-Enabled Dashboard.

The AI-enabled glaucoma dashboard, developed using a large VF dataset containing a broad spectrum of visual deficit types, has the potential to provide clinicians with a user-friendly tool for determination of the severity of glaucomatous…

Association of a Primary Open-Angle Glaucoma Genetic Risk Score With Earlier Age at Diagnosis.

A higher dose of POAG risk alleles was associated with an earlier age at glaucoma diagnosis.

iStent inject trabecular micro-bypass stents with topical prostaglandin as standalone treatment for open-angle glaucoma: 4-year outcomes.

Combining iStent inject implantation with topical prostaglandin produced significant and safe 4-year IOP and medication reductions in OAG.

Predicting Global Test-Retest Variability of Visual Fields in Glaucoma.

Inclusion of archetype VF loss patterns and TD values based on first VF improved the prediction of the global test-retest variability than using traditional global VF indices alone.

Adherence to Follow-up Recommendations Among Individuals in the Philadelphia Glaucoma Detection and Treatment Project.

This study demonstrates that individuals living in underserved urban communities would take advantage of free eye exams in community sites and return for follow-up eye exams in these same settings.

Lessons Learned From 2 Large Community-based Glaucoma Screening Studies.

This editorial highlights lessons learned from 2 large prospective trials: the Philadelphia Telemedicine Glaucoma Detection and Follow-up Study and the Screening To Prevent Glaucoma Study.

Philadelphia Telemedicine Glaucoma Detection and Follow-up Study: Analysis of Unreadable Fundus Images.

Understanding the causes of unreadable fundus images will foster improvements in telemedicine techniques to optimize the predictive accuracy, efficiency, and cost in ophthalmology.

What Glaucoma Patients Are Reading on the Internet: A Systematic Analysis of Online Glaucoma Content.

The most readily accessible online information about glaucoma varies in content, quality, accuracy, navigability, and readability. This systematic analysis identifies potential areas of improvement.

Ahmed Versus Baerveldt Glaucoma Drainage Device in Uveitic Glaucoma: A Retrospective Comparative Study.

Higher complete success rate and significantly greater reduction in mean IOP and number of medications were observed in the Baerveldt group, but with a higher rate of complications including hypotony.

Marijuana and Glaucoma: A Social Media Content Analysis.

Despite American Academy of Ophthalmology, Canadian Ophthalmological Society, and American Glaucoma Society statements against MC use in patients with glaucoma, a significant portion of online material recommends its use.

Outcomes of Valved and Nonvalved Tube Shunts in Neovascular Glaucoma.

Eyes with AGV and BGI had comparable outcomes in NVG, although fewer medications were required in BGI eyes to control IOP.

Baseline Age and Mean Deviation Affect the Rate of Glaucomatous Vision Loss.

Older age and worse MD at baseline are associated with more rapid VF progression in this large dataset.

Reoperation for complications within 90 days of minimally invasive glaucoma surgery.

The rate of reoperation within the first 90 days after MIGS was low. Elevated IOP and complications associated with gel microstents were the main indications for reoperation.

Development and Comparison of Machine Learning Algorithms to Determine Visual Field Progression.

MLCs showed a moderate to high level of accuracy, sensitivity, and specificity and were more balanced than conventional algorithms.

Vision-related Performance and Quality of Life of Patients With Rapid Glaucoma Progression.

Factors associated with rapid glaucoma progression included worse VF MD decreased scores of performance-based measures and subjectively worse VRQoL. After 1 year, rapid progressors had a significant reduction in contrast sensitivity as measured by SPARCS.

Outcomes of trabecular microbypass surgery: Comparison of resident trainees and attending surgeons.

Microbypass stent implantation by resident trainees with attending supervision had similar efficacy and safety as surgery performed by attending surgeons.

Philadelphia Telemedicine Glaucoma Detection and Follow-up Study: Intraocular Pressure Measurements Found in a Population at High Risk for Glaucoma.

In this telemedicine vision screening setting, having a higher IOP at the screening visit increased the likelihood of receiving a final diagnosis of glaucoma.

GLP-1 Receptor Agonists Use and Incidence of Glaucoma: A Systematic Review and Meta-Analysis.

This systematic meta-analysis found that GLP-1 RA use is associated with reduced glaucoma development in retrospective studies.

Early Experience with Netarsudil in Pediatric Patients: A Retrospective Case Series.

Surgical Cancellations in Glaucoma Practice: Causes, Delays, and Effect on Patient Care and Revenue.

This study highlights a significant number of cancellations in a glaucoma practice, most of which occurred within 1 day of planned surgery.

Correlation between Central Visual Field Defects and Stereopsis in Patients with Early-to-Moderate Visual Field Loss.

Central visual field defects were associated with increased odds of poor stereoacuity in patients with early-to-moderate glaucomatous VF loss.

Descriptive Analysis of United States Glaucoma Fellowship Program Directors.

Variability and Power to Detect Progression of Different Visual Field Patterns.

Time to detect central VF progression was reduced with 10-2 MD compared with 24-2 and C24-2 MD in glaucoma eyes in this large dataset, in part because 10-2 tests had lower variability.

Hemorrhagic Complications Following Trabecular Bypass Microstent Surgery in the Setting of Antithrombotic Therapy.

Hemorrhagic complications after trabecular bypass microstent surgery were limited to transient hyphema and were not associated with chronic ATT use. Stent type and female sex were associated with hyphema.

Kahook Dual Blade Goniotomy Versus iStent Implantation Combined With Phacoemulsification: A Systematic Review and Meta-Analysis.

KDB goniotomy may offer better surgical success compared with Stent implantation when used in combination with phacoemulsification.

A Novel Surgical Technique for Ahmed Glaucoma Valve Implantation Without Plate Sutures.

The comparison of short and mid-term outcomes of patients undergoing AGV implantation using both techniques showed similar outcomes and success rates.

Inter-Eye Association of Visual Field Defects in Glaucoma and Its Clinical Utility.

VF patterns of the worse eye are predictive of VF defects in the better eye.

Adherence and Persistence on Prostaglandin Analogues for Glaucoma: A Systematic Review and Meta-Analysis.

Suboptimal adherence and persistence with PGAs are common, with further decreases as duration lengthens. These findings may underscore the value of procedural glaucoma treatments that do not depend on daily patient engagement with topical medications.

Beliefs and Attitudes of Ophthalmologists Regarding SLT as First Line Therapy for Glaucoma.

A better understanding of the barriers for utilizing SLT as a first line therapy provides valuable information to help increase the adoption of this safe and effective procedure.

Transformer-Based Deep Learning Prediction of 10-Degree Humphrey Visual Field Tests From 24-Degree Data.

The predicted 10-2 VF has the potential to improve glaucoma diagnosis.

10-Year Clinical Outcomes of Tube Shunt Surgery at a Tertiary Care Center.

Many eyes maintained IOP control 10 years following TS, but 56% met failure criteria, 39% had substantial vision loss, and 34% underwent additional surgery. Outcomes did not differ with TS model.

Improving Visual Field Forecasting by Correcting for the Effects of Poor Visual Field Reliability.

Including all VFs in the trend estimation has more predictive power for future reliable VFs than excluding unreliable VFs. Correcting for VF reliability further improves model accuracy.

Utility of Optical Coherence Tomography (OCT) in Centers For Medicare and Medicaid Services (CMS)-defined Severe Glaucoma Patients.

Our data demonstrate a substantial portion of eyes with CMS-defined severe glaucoma have measurable RNFL above the floor in at least 1 vertical quadrant that may be longitudinally monitored for progression.

Preliminary Steps to Address Glaucoma Medication Adherence: Beginning to Tackle the Elephant in the Room.

Transscleral Cyclophotocoagulation for Glaucoma in the Setting of Uveal Melanoma.

Gap Analysis of Standard Automated Perimetry Concept Representation in Medical Terminologies.

There is a lack of representation of some SAP data elements in standardized medical terminologies, hampering interoperability and data sharing.

Empowering Family Glaucoma Risk Communication Using QR-Code-Mediated Online Intervention.

This innovative online method of communicating the risk of glaucoma to FDRs of probands prompted and increased the comfort level of familial discussions of glaucoma.

Clinicians' Use of Quantitative Information while Assessing the Rate of Functional Progression in Glaucoma.

Expert academic glaucoma specialists' assessment of the rate of change correlated best with VFI rates, except in eyes with a VFI near the ceiling of 100%.

Clinicians' Use of Quantitative Information When Assessing the Rate of Structural Progression in Glaucoma.

The rate of change of RNFLT in the most rapidly changing sector predicted experts' assessment of the rate of structural progression better than global rates or MRW.

PyOPV: An Open-Source Python Package for Ophthalmic Visual Field Data Management.

PyOPV provides an efficient solution for handling ophthalmic visual field data, bridging a critical gap in data interoperability and research scalability.

Dual-Level Pattern Tree for Visual Field Improves Glaucoma Progression and Polygenic Risk Prediction.

Trunk-branch VF classifiers were superior to trunk-only characterizations for predicting functional progression and glaucoma PRS.

The Impact of Myopia on Regional Visual Field Loss and Progression in Glaucoma.

Lower SE values are associated with worse paracentral VF loss. Worse myopia is associated with functional progression, even when excluding patients with high myopia.

Early Postoperative Aqueous Suppression Therapy and Surgical Outcomes of Ahmed Tube Shunts in Refractory Glaucoma.

Early use of aqueous suppressants may lower the risk of HP and improve AGV outcomes. FINANCIAL DISCLOSURE(S): Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.

In Reply: A Novel Surgical Technique for Ahmed Glaucoma Valve Implantation Without Plate Sutures.

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Consultation Section: Glaucoma. January consultation #3.

A Comparative Study of the Water Drinking Test in Eyes With Open-Angle Glaucoma and Prior Trabeculectomy or Tube Shunt.

Subjects who had undergone either trabeculectomy or tube shunt surgery showed a similar IOP response to the WDT. Subjects on systemic antihypertensive medications experienced significantly greater IOP fluctuations during the test.

Bilateral Same-day Laser Peripheral Iridotomy in the Philadelphia Glaucoma Detection and Treatment Project.

Performing bilateral, same-day LPI was well tolerated in a large community-based, glaucoma detection and treatment project.

The Wills Eye Glaucoma App: Interest of Patients and Their Caregivers in a Smartphone-based and Tablet-based Glaucoma Application.

Glaucoma patients and their caregivers were very interested in using a Glaucoma App; however, many were not willing to spend $3 for an App they seem to value.

Development of Visual Field Screening Procedures: A Case Study of the Octopus Perimeter.

Our method gives a principled approach to choosing between the many parameters of a visual field screening procedure.

Evaluation of Nonmydriatic Hand-held Optic Disc Photography Grading in the Philadelphia Glaucoma Detection and Treatment Project.

Nonmydriatic, monoscopic disc photographs obtained by a hand-held camera had only moderate disc grading reproducibility.

Color Reflectivity Discretization Analysis of OCT Images in the Detection of Glaucomatous Nerve Fiber Layer Defects.

In this study, the novel CORDA HR1 differentiated between normal subjects and glaucoma suspects more accurately than Cirrus RNFL, and in temporal and nasal regions when discriminating between normal and glaucomatous eyes.

Water-drinking test in primary angle-closure suspect before and after laser peripheral iridotomy.

Primary angle-closure suspects who underwent the water-drinking test had a slightly more pronounced recovery of intraocular pressure after the laser peripheral iridotomy was performed, which may be attributed to increase in the area of exposed trabecular meshwork following treatment.

Twenty-four-hour intraocular pressure measurement in glaucoma.

Evaluation of Risk Factors for Glaucoma Drainage Device-related Erosions: A Retrospective Case-Control Study.

History of concomitant intraocular surgery with GDD implantation may be a potential risk factor for future erosions.

Needle bleb revision with bevacizumab and mitomycin C compared with mitomycin C alone for failing filtration blebs.

There was no significant difference between the success rates and IOPs at postoperative month 6 between treatment and control groups. Postoperative blebs in the treatment group were less vascular and had greater extent.

A comparison of methods used to evaluate mobility performance in the visually impaired.

A validated scoring system based on errors is more effective when assessing visual disability during mobility testing than recording the time taken for course completion.