Jack Phu

Clinical Evaluation of Swedish Interactive Thresholding Algorithm-Faster Compared With Swedish Interactive Thresholding Algorithm-Standard in Normal Subjects, Glaucoma Suspects, and Patients With Glaucoma.

After accounting for different rates of test reliability, SFR can result in significant time savings compared with SS.

Comparison of 10-2 and 24-2C Test Grids for Identifying Central Visual Field Defects in Glaucoma and Suspect Patients.

The 24-2C and 10-2 test grids return similar global indices of visual field performance and proportionally similar amounts of central visual field loss.

Ability of 24-2C and 24-2 Grids to Identify Central Visual Field Defects and Structure-Function Concordance in Glaucoma and Suspects.

The 24-2C returned global visual field indices similar to the 24-2 grid but tended to identify more clusters of central functional defects.

Pattern Recognition Analysis Reveals Unique Contrast Sensitivity Isocontours Using Static Perimetry Thresholds Across the Visual Field.

Cluster analysis reveals statistically significant groups of test locations within the 30-2 test grid exhibiting the same age-related decline.

Consistency of Structure-Function Correlation Between Spatially Scaled Visual Field Stimuli and In Vivo OCT Ganglion Cell Counts.

Stimulus sizes within critical spatial summation area (GI-II) improved structure-function correlations in the central visual field.

Viability of Performing Multiple 24-2 Visual Field Examinations at the Same Clinical Visit: The Frontloading Fields Study (FFS).

Frontloading using SITA-Faster was viable for obtaining sets of reliable, repeatable perimetric data in terms of conventional outputs, overcoming practical issues regarding low test reliability using singleton results and confirmation of visual field defects.

Visualizing the Consistency of Clinical Characteristics that Distinguish Healthy Persons, Glaucoma Suspect Patients, and Manifest Glaucoma Patients.

Despite advances in quantitative ocular imaging and perimetry, the transition among healthy, glaucoma suspect, and manifest glaucoma patients remains confounded by a lack of consistent, reproducible combinations of quantitative clinical criteria.

Frontloading SITA-Faster Can Increase Frequency and Reliability of Visual Field Testing at Minimal Time Cost.

Frontloading VFs using SFR produced sets of repeatable perimetric data with significant improvement of reliability indices from the first to second test.

The Frontloading Fields Study: The Impact of False Positives and Seeding Point Errors on Visual Field Reliability When Using SITA-Faster.

Current criteria for judging an unreliable VF result (FP rate >15% and SPE) can lead to data being erroneously excluded, as many results do not show significant differences compared to those deemed "reliable." Censoring of…

The Frontloading Fields Study (FFS): Detecting Changes in Mean Deviation in Glaucoma Using Multiple Visual Field Tests Per Clinical Visit.

Performing two tests per clinical visit at 6 months is practical using SITA-Faster and provides higher detection rates of mean deviation change in comparison with only one test performed per visit and more spaced-out intervals.

Reducing Spatial Uncertainty Through Attentional Cueing Improves Contrast Sensitivity in Regions of the Visual Field With Glaucomatous Defects.

Sensitivity measurements across the VF are negatively affected by spatial uncertainty, which increases with greater VF loss. Minimizing uncertainty can improve sensitivity at locations of deficit.

A Method Using Goldmann Stimulus Sizes I to V-Measured Sensitivities to Predict Lead Time Gained to Visual Field Defect Detection in Early Glaucoma.

Our model predicted substantial lead time differences when using stimulus sizes within or near Ac. Such stimulus sizes could potentially detect VF defects, on average, 4 years earlier than current paradigms.

Standard automated perimetry for glaucoma and diseases of the retina and visual pathways: Current and future perspectives.

This also formed the basis for our clustering framework, which groups together statistically similar structural and functional test locations to maximise structure-function concordance.

Evaluation of the Consistency of Glaucomatous Visual Field Defects Using a Clustered SITA-Faster Protocol.

Frontloading SFR tests can provide repeatable data for the evaluation of the consistency of pattern deviation defects in glaucoma, with no observable decline in performance from test fatigue.

A Strategy for Seeding Point Error Assessment for Retesting (SPEAR) in Perimetry Applied to Normal Subjects, Glaucoma Suspects, and Patients With Glaucoma.

SPEs contribute to a large proportion of unreliable visual field test results, particularly when using SITA-Faster.

Quantification and Predictors of Visual Field Variability in Healthy, Glaucoma Suspect, and Glaucomatous Eyes Using SITA-Faster.

The variability of SFR increases with worsening threshold sensitivity, is stable over time, and is greater for peripheral compared with central test locations.

Remote Grading of the Anterior Chamber Angle Using Goniophotographs and Optical Coherence Tomography: Implications for Telemedicine or Virtual Clinics.

Although moderate agreement between graders and ground truth could be obtained under binary evaluations, angle grades were generally underestimated. Factors affecting concordance were primarily the extremes of the ground truth angle and iris contour.

Glaucoma Suspects: The Impact of Risk Factor-Driven Review Periods on Clinical Load, Diagnoses, and Healthcare Costs.

The stringency of risk assessments for glaucoma suspects impacts review periods and therefore clinical load, healthcare costs, and diagnosis rates.

ChatGPT for Addressing Patient-centered Frequently Asked Questions in Glaucoma Clinical Practice.

ChatGPT-3.5 responses to FAQs in glaucoma were generally agreeable in terms of coherency, factuality, comprehensiveness, and safety.

Differences in Static and Kinetic Perimetry Results are Eliminated in Retinal Disease when Psychophysical Procedures are Equated.

Clinical SKD found using clinical techniques is due to methodologic differences and criterion bias, and is eliminated by using an equated and more objective psychophysical task, similar to normal subjects.

Clinical Evaluations of Macular Structure-Function Concordance With and Without Drasdo Displacement.

With GCA deviation maps, small improvements in structure-function concordance were observed without displacement, which are unlikely to be clinically meaningful. Using GCIPL thickness data, significantly better structure-function concordance was observed centrally with Drasdo displacement.

How Many Subjects are Needed for a Visual Field Normative Database? A Comparison of Ground Truth and Bootstrapped Statistics.

Ground truth statistics of VF sensitivities could be approximated using set sizes that are significantly smaller than the original cohort.

Application of Pattern Recognition Analysis to Optimize Hemifield Asymmetry Patterns for Early Detection of Glaucoma.

A clustering map derived using CSIs improved detection of glaucomatous VFs compared with the currently available GHT. An optimized CSI-derived map may serve as an additional means to aid earlier detection of glaucoma.

Longitudinal variability outcomes of frontloaded visual field testing.

Frontloading VF tests on the same visit may help clinicians meet the recommendations of minimum test frequency in glaucoma and can decrease the longitudinal variability of global and pointwise sensitivity changes.

The Frontloading Approach to Meet Guideline-Recommended Visual Field Testing for Glaucoma: Time and Cost.

A frontloading approach and SITA-Faster paradigm led to patients attaining 6 reliable VFs over 14 months sooner than non-frontloaded, with >84% receiving the recommended number of 6 tests in the first 2 years.

Visual Field Progression Rates in Glaucoma: Frontloaded Versus Clinical Standard (Nonfrontloaded) SITA-Faster.

Frontloaded (two 24-2 SITA-Faster VF tests per eye per visit) tests detected more than twice the number of glaucoma progressors based on MD slopes in a cohort of patients with predominantly early glaucoma, compared with the clinical standard (1 VF per eye per visit).

Prediction of repeatable glaucomatous visual field defects based on cluster characteristics.

The location, size and volume of clusters of defects on an initial VF test may be predictive of subsequent repeatability. This may help distinguish eyes with a higher risk of repeatable defects.

Quantitative Classification of Visual Field Defects in Early Glaucoma.

In a large cohort of suspect and early glaucoma, the most common VF defects were nasal step, enlarged blind spot and arcuate defects, with a significant difference in distribution between initial versus repeatable defects and reliable versus unreliable tests.