Chapter 45: Minimally Invasive Glaucoma Surgery (MIGS)

Rocks Madeline C, Dossantos Jason, Tran Hoang-Viet et al.

This study found OMNI canaloplasty with or without a Hydrus microstent during cataract surgery yielded comparable IOP, medication, and success rates at one year, suggesting the microstent may not add significant benefit.

Okada Yo, Mori Kazuhiko, Yoshii Kengo et al.

PreserFlo alone was safe for corneal endothelium across glaucoma types, but combining it with cataract surgery increased endothelial cell loss, especially in pseudoexfoliation glaucoma, impacting surgical planning.

Tan Nicholas E, Young Cara E Capitena, Seibold Leonard K

This review found trabecular bypass stents and canaloplasty effectively lower IOP and medication needs in glaucoma, with stents having more long-term data but canaloplasty offering similar efficacy without implant issues.

Ang Bryan Chin Hou, Betzler Bjorn Kaijun, Sim Jackie Jia Lin et al.

Phaco-Hydrus in NTG eyes sustainedly reduced glaucoma medication burden over 36 months, without significant IOP reduction. This suggests its role is primarily medication reduction, not IOP lowering.

Pathak Anand Kumar, Ganesh Meghna, Virani Baiju et al.

Sharkawi Eamon, Artes Paul H, Dari Maria Laura et al.

Uzel Mehmet Murat, Koçer Ali Mert, Aksoy Bekir Eren et al.

Trabecular meshwork peeling during hemi-GATT significantly reduces early postoperative IOP spikes, improving early IOP control without compromising surgical success, offering a safer procedure.

Xie Bin, Yang Zefeng, Wang Zhixuan et al.

Goniotomy and phacogoniotomy are effective, safe, and widely applicable glaucoma surgeries, especially valuable in resource-limited settings due to their non-device-built nature.

Baba Taro, Okada Naoki, Tokumo Kana et al.

This study found ciliochoroidal detachment is common after Preserflo MicroShunt surgery. Short axial length and postoperative hypotony are key risk factors, informing patient selection and monitoring.

Ansari Abdus Samad, Jung Minsu, Hamdan Amar et al.

This study found many statistically significant MIGS trial outcomes are statistically fragile, often due to few events, highlighting the need for cautious interpretation of reported efficacy.

Orenc Pinar, Kuçukbezirci Guldeniz Usta, Gungel Hulya

This study found combined phacoemulsification and HFDS successfully lowered IOP. Postoperative AS-OCT showed angle widening, with 750-µm posterior angle measurements potentially indicating surgical success, aiding long-term glaucoma follow-up.

Iemura Hiroki, Yoshimoto Sota, Sugisawa Keigo et al.

Preserflo MicroShunt effectively lowered glaucoma eye pressure, but less so in highly myopic eyes, indicating reduced short-term success and suggesting axial length is a key surgical risk factor.

Mohapatra Avilasha, Suresh Vyshak, Kaushik Sushmita

M Priyanga, Rajamani Muralidhar, Grover Davinder S et al.

This study found globe rotation with a direct goniolens for ab interno bleb revision successfully accessed the superior angle, significantly lowering IOP and medication use, offering a practical alternative for glaucoma surgery.

Dada Tanuj, Beri Nitika

Choo Dominic Moogon, Durham Tyler Avery, Zhang Hongyi et al.

Real-world iStent data showed distinct complication profiles across generations, with malposition and elevated IOP common. This highlights the need for tailored surgical vigilance for specific iStent types.

Kaliche Mohammed-Nabil, Vienne-Jumeau Aliénor, Hallali Gabriel et al.

This study found the Preserflo MicroShunt effectively lowered intraocular pressure in refractory ocular hypertension/secondary glaucoma after vitrectomy, showing significant IOP reduction and a favorable safety profile for these challenging cases.

Neelambika Kulkarni, Pegu Julie, Khan Mazhar et al.

Ventura-Abreu Néstor, Molins Blanca, Guerra-Meniconi José et al.

This study found successful XEN45 blebs correlate with higher preoperative goblet cell density and mucin, and AS-OCT best monitors postoperative bleb function for clinical management.