Optic disc haemorrhage and primary open-angle glaucoma: a clinical review.
Jasty Uma, Harris Alon, Siesky Brent, Rowe Lucas W, Verticchio Vercellin Alice C, Mathew Sunu, Pasquale Louis R
AI Summary
This review found optic disc hemorrhage is a significant risk factor for primary open-angle glaucoma across populations, highlighting its importance for understanding glaucoma pathogenesis and treatment.
Abstract
Studies have confirmed that optic disc haemorrhage (ODH) is a significant risk factor for the development and progression of primary open-angle glaucoma (POAG). Various populations have differing risk factors for developing POAG. As such, a literature review was conducted examining seven studies published in India, China, Japan, Australia, Korea and the USA. The goal of this review was to better identify ODH risk factors and their relationship to development and progression of POAG. Ultimately, patients with ODH have a greater risk for developing POAG across all populations analysed in this review. However, some populations demonstrated additional risk factors for ODH, such as increasing age and female gender. Paradoxically, data from several studies show that people of African descent have a reduced risk of ODH despite having increased risk of open-angle glaucoma than their Caucasian counterparts. By parsing out the complex relations between ODH and open-angle glaucoma stratified by age, gender and race, we may gain a broader understanding of glaucoma pathogenesis and derive individualised treatment strategies.
MeSH Terms
Shields Classification
Key Concepts4
Optic disc haemorrhage (ODH) is a significant risk factor for the development and progression of primary open-angle glaucoma (POAG).
Patients with optic disc haemorrhage (ODH) have a greater risk for developing primary open-angle glaucoma (POAG) across all populations analyzed in a literature review of seven studies from India, China, Japan, Australia, Korea, and the USA.
Some populations demonstrated additional risk factors for optic disc haemorrhage (ODH), such as increasing age and female gender, based on a literature review of seven studies from India, China, Japan, Australia, Korea, and the USA.
Data from several studies show that people of African descent have a reduced risk of optic disc haemorrhage (ODH) despite having an increased risk of open-angle glaucoma than their Caucasian counterparts.
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