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Curr Opin OphthalmolDecember 20244 citations

Minimally invasive glaucoma surgery in angle closure.

Chan Nicole Shu-Wen, Sng Chelvin C A


AI Summary

Combining cataract surgery with MIGS for angle-closure glaucoma shows promise for better IOP and medication reduction than cataract surgery alone, offering a safer alternative to traditional surgeries.

Abstract

Purpose of review: This review discusses the evidence on the efficacy, safety and role of minimally invasive glaucoma surgery (MIGS) in eyes with angle closure glaucoma. While cataract surgery remains the most established surgical treatment for primary angle closure glaucoma (PACG), the intraocular pressure (IOP) may remain elevated after cataract surgery despite open angles due to trabecular meshwork damage from chronic iridotrabecular contact.

Recent findings: There is emerging evidence that combining cataract surgery with MIGS in eyes with PACG, though an off-label indication for some MIGS devices, can achieve greater IOP and glaucoma medication reduction than cataract surgery alone.

Summary

Trabecular bypass MIGS procedures and less destructive forms of ciliary body treatment have been shown to be effective in PACG and are safer alternatives to traditional incisional surgeries. Evidence for the use of subconjunctival MIGS and suprachoroidal MIGS in angle closure eyes is lacking at present, and further investigation is indicated.


MeSH Terms

HumansGlaucoma, Angle-ClosureMinimally Invasive Surgical ProceduresIntraocular PressureTrabecular MeshworkFiltering SurgeryTrabeculectomy

Key Concepts6

Combining cataract surgery with minimally invasive glaucoma surgery (MIGS) in eyes with primary angle closure glaucoma (PACG) can achieve greater intraocular pressure (IOP) and glaucoma medication reduction than cataract surgery alone, despite some MIGS devices being off-label for this indication.

Comparative EffectivenessReviewEmerging Evidence Reviewn=Not specifiedCh13Ch45

Trabecular bypass MIGS procedures and less destructive forms of ciliary body treatment have been shown to be effective in primary angle closure glaucoma (PACG).

TreatmentReviewn=Not specifiedCh13

Trabecular bypass MIGS procedures and less destructive forms of ciliary body treatment are safer alternatives to traditional incisional surgeries for primary angle closure glaucoma (PACG).

Comparative EffectivenessReviewn=Not specifiedCh13Ch40

Evidence for the use of subconjunctival MIGS and suprachoroidal MIGS in angle closure eyes is currently lacking, and further investigation is indicated.

MethodologyExpert OpinionReviewn=Not specifiedCh13

Cataract surgery remains the most established surgical treatment for primary angle closure glaucoma (PACG).

TreatmentReviewn=Not specifiedCh13Ch45

Despite open angles after cataract surgery, intraocular pressure (IOP) may remain elevated in primary angle closure glaucoma (PACG) due to trabecular meshwork damage from chronic iridotrabecular contact.

MechanismReviewn=Not specifiedCh2Ch13

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