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Section III · Management

Chapter 44: Surgical Approaches for Coexisting Glaucoma and Cataract

Shields' Textbook of Glaucoma, 6th edition

Showing 1–20 of 1,392 articles

6.
Case Series

Clinical outcomes of Preserflo MicroShunt implant procedure in open‑angle glaucoma patients - a 1000 eyes case-series; including subanalysis of combined cataract-glaucoma surgery and standalone surgery in pseudophakic eyes.

Klabe Karsten, Werth Jan Philipp, Kaymak Hakan et al.

Graefes Arch Clin Exp OphthalmolMar 2026

This study found the Preserflo MicroShunt effectively and safely lowered eye pressure long-term in open-angle glaucoma patients, including those with combined cataract surgery or pseudophakia, supporting its real-world use.

12.
Systematic Review

Goniotomy and phacogoniotomy in glaucoma surgery.

Xie Bin, Yang Zefeng, Wang Zhixuan et al.

Asia Pac J Ophthalmol (Phila)Mar 2026

Goniotomy and phacogoniotomy are effective, safe, and widely applicable glaucoma surgeries, especially valuable in resource-limited settings due to their non-device-built nature.

13.
Observational Study

Anterior Chamber Angle Changes and Surgical Outcomes After Combined Phacoemulsification and High-Frequency Deep Sclerotomy: A Prospective AS-OCT Study.

Orenc Pinar, Kuçukbezirci Guldeniz Usta, Gungel Hulya

J GlaucomaFeb 2026

This study found combined phacoemulsification and HFDS successfully lowered IOP. Postoperative AS-OCT showed angle widening, with 750-µm posterior angle measurements potentially indicating surgical success, aiding long-term glaucoma follow-up.

15.
Prospective Study

The extent of peripheral anterior synechiae and efficacy of combined phacoemulsification and goniosynechialysis in primary angle-closure glaucoma and cataracts: A multicenter prospective study.

Xiong Kun, Wang Yachen, Yu Bo et al.

Asia Pac J Ophthalmol (Phila)Jan 2026

This study found that combined cataract surgery and goniosynechialysis effectively lowered eye pressure in angle-closure glaucoma, regardless of initial synechiae extent, suggesting broad applicability.

19.
Retrospective Study

Cataract Surgery with IOL Implantation in Children with Chronic Anterior Uveitis Associated with Juvenile Idiopathic Arthritis (JIA) or Antinuclear Antibody (ANA)-Positive Uveitis: Mid-term Results and Predictors for Outcome.

Wortmann Charlotte, Backes Johanna, Rothaus Kai et al.

Am J OphthalmolDec 2025

Cataract surgery with IOLs in children with JIA/ANA-positive uveitis improved vision, but careful uveitis control and tailored surgery are crucial for good outcomes and managing complications like glaucoma.

20.
Randomized Controlled Trial

Anterior chamber flare and central macular thickness after trabeculectomy versus after phacoemulsification.

Ahmed Yasmeen, Erichsen Jesper Høiberg, Ahmadzadeh Afrouz et al.

Acta OphthalmolNov 20251 citations

This study compared inflammation and macular thickness after trabeculectomy vs. phacoemulsification. Both procedures caused similar early inflammation, but phacoemulsification led to a significantly greater and more persistent increase in macular thickness.

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The overall 2-year failure rate for trabeculectomy was 50.6%, for tube shunt surgery was 52.1%, for goniotomy was 53.3%, and for canaloplasty was 49.0% among 2483 eyes with secondary glaucoma aged 18 to 40 years.

TreatmentCohortRetrospective clinical cohort studyn=2483 eyes

Minimally invasive glaucoma surgery (MIGS) accounted for nearly one in five of the glaucoma surgeries recorded in young patients with secondary glaucoma, with approximately half of cases remaining failure-free at 2 years.

EpidemiologyCohortRetrospective clinical cohort studyn=454 MIGS, 337 trabeculectomies, and 1692 tube shunt surgeries

In uveitic glaucoma, the 2-year failure rates were 56.0% for trabeculectomy, 45.6% for tube shunt surgery, 55.1% for goniotomy, and 35.9% for canaloplasty.

TreatmentCohortRetrospective clinical cohort studyn=2483 eyes

In primary open-angle glaucoma (POAG) patients, iTrack ab-interno canaloplasty and iStent trabecular micro-bypass implantation showed no statistically significant differences in effectiveness outcomes.

Comparative EffectivenessCohortAmbispective cohort studyn=339 eyes (iStent: n=115; iTrack: n=224)

In primary open-angle glaucoma (POAG) patients, both iTrack ab-interno canaloplasty and iStent trabecular micro-bypass implantation had favourable safety profiles with infrequent and self-limited complications, no sight-threatening events, and low reoperation rates.

TreatmentCohortAmbispective cohort studyn=339 eyes (iStent: n=115; iTrack: n=224)

More eyes were medication-free in the iTrack ab-interno canaloplasty group (42%) compared to the iStent trabecular micro-bypass implantation group (29%) in primary open-angle glaucoma (POAG) patients (p=0.029).

Comparative EffectivenessCohortAmbispective cohort studyn=339 eyes (iStent: n=115; iTrack: n=224)

In primary open-angle glaucoma (POAG) patients, mean intraocular pressure (IOP) and medication usage decreased from 17.3 ± 4.2 mmHg and 2.0 ± 1.1 at baseline to 14.2 ± 3.5 mmHg and 1.3 ± 1.1 in the iStent trabecular micro-bypass group (p<0.001) over a mean follow-up of 27.2 ± 14.5 months.

TreatmentCohortAmbispective cohort studyn=115 eyes

In primary open-angle glaucoma (POAG) patients, mean intraocular pressure (IOP) and medication usage decreased from 16.9 ± 5.0 mmHg and 2.0 ± 1.1 at baseline to 14.3 ± 3.4 mmHg and 1.1 ± 1.3 in the iTrack ab-interno canaloplasty group (p<0.001) over a mean follow-up of 20.3 ± 7.7 months.

TreatmentCohortAmbispective cohort studyn=224 eyes

PreserFlo™ MicroShunt implantation significantly reduced mean intraocular pressure (IOP) from 24.29±6.05 mmHg to 17.95±8.22 mmHg (P < 0.001) in 34 eyes from 27 children (mean age 4.9 ± 3.6 y) with refractory childhood glaucoma.

TreatmentCohortRetrospective studyn=34 eyes from 27 patients

PreserFlo™ MicroShunt implantation significantly reduced mean IOP-lowering medication numbers from 3.0±0.0 to 0.9±1.3 (P < 0.001) in 34 eyes from 27 children (mean age 4.9 ± 3.6 y) with refractory childhood glaucoma.

TreatmentCohortRetrospective studyn=34 eyes from 27 patients

Overall success of PreserFlo™ MicroShunt implantation was 61.70% in 34 eyes from 27 children with refractory childhood glaucoma, with 50% achieving complete success (IOP <21 mmHg and ≥25% IOP reduction without medications) at an average follow-up time of 13.92±4.85 months.

TreatmentCohortRetrospective studyn=34 eyes from 27 patients

The survival rates of PreserFlo™ MicroShunt implantation in refractory childhood glaucoma declined to 53% at 12 months and 33% at 24 months in 34 eyes from 27 children.

PrognosisCohortRetrospective studyn=34 eyes from 27 patients