Anterior Segment Optical Coherence Tomography and Anterior Segment Optical Coherence Tomography Angiography After Bleb Forming Glaucoma Surgeries: A Systematic Review.
Kallab Martin, Huang Alex S, Bolz Matthias, Strohmaier Clemens A
AI Summary
This review found AS-OCT/AS-OCTA shows promise for assessing glaucoma bleb function after surgery, but inconsistent study methods currently limit its routine clinical application.
Abstract
Background
The bleb-forming surgical spectrum in open-angle glaucoma has recently been expanded by novel surgical approaches. Through a medical device implantation (Xen Gel Stent (XGI) or Preserflo Microshunt (PMI)), these procedures aim at more standardised aqueous humour shunting and an intra- and postoperative risk reduction. Postoperatively, however, XEN, PMI and trabeculectomy share their dependence on the proper function of the filtration bleb. This review summarises available literature on anterior segment optical coherence tomography (AS-OCT)- and AS-OCT angiography (AS-OCTA)-based bleb parameters with an emphasis on their association with bleb function.
Methods
A systematic PubMed search was performed to identify the available evidence.
Results
A total of 52 suitable reports were identified and are presented in a structured manner.
Conclusion
The retrieved literature demonstrates that there exists a broad body of evidence for the use of AS-OCT and AS-OCTA after TE, XGI and PMI with the potential for AS-OCT and AS-OCTA enhanced follow-up plans. Their implementation in clinical routine is, however, currently impaired by highly variable and impractical study endpoints, lacking transferability of available evidence between different surgical procedures and missing evidence from prospective interventional trials.
MeSH Terms
Shields Classification
Key Concepts5
There is a broad body of evidence for the use of anterior segment optical coherence tomography (AS-OCT) and AS-OCT angiography (AS-OCTA) after trabeculectomy (TE), Xen Gel Stent (XGI), and Preserflo Microshunt (PMI), with potential for AS-OCT and AS-OCTA enhanced follow-up plans.
The implementation of anterior segment optical coherence tomography (AS-OCT) and AS-OCT angiography (AS-OCTA) in clinical routine is impaired by highly variable and impractical study endpoints, lacking transferability of available evidence between different surgical procedures, and missing evidence from prospective interventional trials.
The bleb-forming surgical spectrum for open-angle glaucoma has been expanded by novel surgical approaches, including medical device implantation with Xen Gel Stent (XGI) or Preserflo Microshunt (PMI), aiming for more standardized aqueous humour shunting and reduced intra- and postoperative risk.
Postoperatively, Xen Gel Stent (XEN), Preserflo Microshunt (PMI), and trabeculectomy all depend on the proper function of the filtration bleb.
A systematic PubMed search identified 52 suitable reports on anterior segment optical coherence tomography (AS-OCT) and AS-OCT angiography (AS-OCTA)-based bleb parameters after bleb-forming glaucoma surgeries.
Related Articles5
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Observational StudyAutomated Gonioscopy Assessment of XEN45 Gel Stent Angle Location After Isolated XEN or Combined Phaco-XEN Procedures: Clinical Implications.
Cross-Sectional StudyBleb Morphology After Needling With Viscoelastic of an Ab Interno Microstent Assessed by Optical Coherence Tomography.
Case SeriesElectron microscopic evaluation of a gold glaucoma micro shunt after explantation.
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