Outcome of Goniotomy Over 120, 240 and 360 Degrees in Juvenile Open Angle Glaucoma: A Multicenter Study.
Zefeng Yang, Zhixuan Wang, Hanying Fan, Qingshu Ge, Guangfu Dang, Xiao Yang, Lin Xie, Xiaoming Zhu, Yangfan Yang, Yuhong Wang, Jinkun Liu, Hongyang Zhang, Yuhan Feng, Yongjun Qi, Xiangxiang Ye, Mingying Lai, Peijie Lin, Pusheng Wang, Shumei Han, Jiangang Xu, Liming Tao, Heting Liu, Xin Nie, Mengfei Liao, Kai Zou, Yi Jiang, Yunhe Song, Fengbin Lin, Fengqi Zhou, Dilimulati Xiaokaiti, Xiaoyi Liu, Zige Fang, Ling Jin, Yu Chen, Clement C Tham, Ying Han, Xiaojing Pan, Liuzhi Zeng, Robert N Weinreb, Xiulan Zhang
Summary
240-degree and 360-degree GT showed similar efficacy in IOP reduction and were superior to 120-degree GT. More extensive GT may provide better outcomes in JOAG.
Abstract
PRCIS
240-degree and 360-degree goniotomy (GT) demonstrated similar efficacy in intraocular pressure (IOP) reduction, both outperforming 120-degree GT in patients with juvenile open angle glaucoma (JOAG) at postoperative 6-month follow-up.
OBJECTIVE
To compare the surgical efficacy and safety of 120-degree, 240-degree, and 360-degree GT for patients with JOAG.
PATIENTS AND METHODS
This multicenter retrospective study included 102 eyes of 102 patients with JOAG, who underwent GT with a follow-up of at least 6 months. Patients were categorized into 3 groups: (1) 120-degree GT, (2) 240-degree GT, and (3) 360-degree GT. IOP, glaucoma medications, and complications were recorded at baseline and the final visit. Complete success and qualified success were defined as a postoperative IOP ≤21 mm Hg without and with medications, respectively.
RESULTS
Mean age of the participants was 24.4 ± 7.9 years. After a mean follow-up of 8.1 ± 2.7 months, complete success rates were similar between the 240-degree GT (45.2%) and the 360-degree GT (63.2%; P = 0.135), and both were superior to 120-degree GT (18.2%; P 0.05). Hyphema was the most common postoperative complication, with a significantly higher incidence in the 360-degree GT (68.4%) compared with the 240-degree GT (41.9%) and 120-degree GT (33.3%; P < 0.05).
CONCLUSIONS
240-degree and 360-degree GT showed similar efficacy in IOP reduction and were superior to 120-degree GT. More extensive GT may provide better outcomes in JOAG.
Keywords
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