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Invest Ophthalmol Vis SciJanuary 201725 citations

Comparison of Aqueous Outflow Facility Measurement by Pneumatonography and Digital Schiøtz Tonography.

Kazemi Arash, McLaren Jay W, Lin Shuai-Chun, Toris Carol B, Gulati Vikas, Moroi Sayoko E, Sit Arthur J


AI Summary

Comparing pneumatonography and Schiøtz tonography for outflow facility, researchers found they correlated but yielded different absolute values (Schiøtz higher), meaning they are not interchangeable for direct clinical comparison.

Abstract

Purpose

It is not known if outflow facilities measured by pneumatonography and Schiøtz tonography are interchangeable. In this study we compared outflow facility measured by pneumatonography to outflow facility measured by digital Schiøtz tonography.

Methods

Fifty-six eyes from 28 healthy participants, ages 41 to 68 years, were included. Intraocular pressure (IOP) was measured in the sitting and supine positions with a pneumatonometer. With the subject in the supine position, IOP was recorded for 2 minutes by using a pneumatonometer with a 10-g weight and for 4 minutes by using a custom digital Schiøtz tonometer. Outflow facility was determined from the changes in pressure and intraocular volume and a standard assumed ocular rigidity coefficient for each instrument, respectively, and by using an ocular rigidity coefficient calculated by measuring pressure without and with a weight added to the pneumatonometer tip.

Results

The outflow facility was 0.29 ± 0.09 μL/min/mm Hg by Schiøtz tonography and 0.24 ± 0.08 μL/min/mm Hg by pneumatonography (P < 0.001) when using the standard assumed constant ocular rigidity coefficient. Mean calculated ocular rigidity coefficient was 0.028 ± 0.01 μL-1, and outflow facility determined by using this coefficient was 0.23 ± 0.08 μL/min/mm Hg by Schiøtz tonography and 0.21 ± 0.07 μL/min/mm Hg by pneumatonography (P = 0.003). Outflow facilities measured by the two devices were correlated when the ocular rigidity was assumed (r = 0.60, P < 0.001) or calculated (r = 0.70, P < 0.001).

Conclusions

Outflow facilities measured by pneumatonography were correlated with those measured by Schiøtz tonography, but Schiøtz tonography reported approximately 10% to 20% higher facilities when using the standard method. When ocular rigidity was determined for each eye, differences were smaller. Measurements from these devices cannot be compared directly.


MeSH Terms

AdultAgedAqueous HumorEquipment DesignFemaleHealthy VolunteersHumansIntraocular PressureMaleMiddle AgedNomogramsPostureReproducibility of ResultsTonometry, Ocular

Key Concepts5

Outflow facility was 0.29  0.09 L/min/mm Hg by Schitz tonography and 0.24  0.08 L/min/mm Hg by pneumatonography (P < 0.001) when using the standard assumed constant ocular rigidity coefficient.

Comparative EffectivenessCross-sectionalCross-sectional studyn=56 eyes from 28 healthy participantsCh3

Mean calculated ocular rigidity coefficient was 0.028  0.01 L-1, and outflow facility determined by using this coefficient was 0.23  0.08 L/min/mm Hg by Schitz tonography and 0.21  0.07 L/min/mm Hg by pneumatonography (P = 0.003).

Comparative EffectivenessCross-sectionalCross-sectional studyn=56 eyes from 28 healthy participantsCh3

Outflow facilities measured by pneumatonography were correlated with those measured by Schitz tonography when the ocular rigidity was assumed (r = 0.60, P < 0.001) or calculated (r = 0.70, P < 0.001).

Comparative EffectivenessCross-sectionalCross-sectional studyn=56 eyes from 28 healthy participantsCh3

Outflow facilities measured by Schitz tonography reported approximately 10% to 20% higher facilities compared to pneumatonography when using the standard method.

Comparative EffectivenessCross-sectionalCross-sectional studyn=56 eyes from 28 healthy participantsCh3

Measurements of outflow facility from pneumatonography and Schitz tonography cannot be compared directly.

Comparative EffectivenessCross-sectionalCross-sectional studyn=56 eyes from 28 healthy participantsCh3

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