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Bejanian Marina

4 articles in GJC

4 articles in GJC

1.

Phase 3, Randomized, 20-Month Study of Bimatoprost Implant in Open-Angle Glaucoma and Ocular Hypertension (ARTEMIS 1).

Medeiros Felipe A, Walters Thomas R, Kolko Miriam, Coote Michael, Bejanian Marina, Goodkin Margot L et al.

OphthalmologyJun 202097 citationsRandomized Controlled Trial

This study found bimatoprost implants effectively lowered IOP like timolol, but the 15μg dose had higher corneal risks. The 10μg implant shows promise for glaucoma adherence, balancing efficacy and safety.

2.

Oral Memantine for the Treatment of Glaucoma: Design and Results of 2 Randomized, Placebo-Controlled, Phase 3 Studies.

Weinreb Robert N, Liebmann Jeffrey M, Cioffi George A, Goldberg Ivan, Brandt James D, Johnson Chris A et al.

OphthalmologyAug 2018112 citationsRandomized Controlled Trial

Two large studies found oral memantine (10mg or 20mg daily) did not prevent glaucoma progression over 48 months compared to placebo, indicating it's not an effective neuroprotective treatment.

4.

Bimatoprost 0.03% preservative-free ophthalmic solution versus bimatoprost 0.03% ophthalmic solution (Lumigan) for glaucoma or ocular hypertension: a 12-week, randomised, double-masked trial.

Day Douglas G, Walters Thomas R, Schwartz Gail F, Mundorf Thomas K, Liu Charlie, Schiffman Rhett M et al.

Br J OphthalmolAug 201340 citationsRandomized Controlled Trial

This study found preservative-free bimatoprost 0.03% is equally effective and safe as standard bimatoprost 0.03% for lowering intraocular pressure in glaucoma/ocular hypertension, offering a new treatment option.

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