Optic Nerve Head Spatial Transcriptomic Change in Nonhuman Primate Early Experimental Glaucoma.
Williams Galen, Lee Jinho, Zangirolani Gabriel, Reynaud Juan, Yang Hongli, Marsh-Armstrong Nicholas et al.
Early glaucoma causes spatially distinct retrolaminar myelin loss and laminar inflammatory/collagen changes in the ONH. This reveals molecular pathogenesis and potential neuroprotective targets.