Stowell Cheri

Chaudhary Priya, Lockwood Howard, Stowell Cheri, Bushong Eric, Reynaud Juan, Yang Hongli et al.

Nonhuman primate glaucoma studies found structurally intact optic nerve axons show significant demyelination. This suggests a novel mechanism of nerve damage in early/moderate glaucoma, impacting vision beyond axon loss.

Chaudhary Priya, Stowell Cheri, Reynaud Juan, Gardiner Stuart K, Yang Hongli, Williams Galen et al.

This NHP study found early glaucoma causes optic nerve myelin loss and increased microglial activity, suggesting these changes are crucial for understanding and treating early glaucoma.

Yang Hongli, Reynaud Juan, Lockwood Howard, Williams Galen, Hardin Christy, Reyes Luke et al.

This monkey study found glaucoma causes optic nerve head connective tissue deformation and remodeling, driven by cellular mechanobiology, leading to nerve damage. This highlights connective tissue as a therapeutic target.