Coote Michael A

Sarossy Marc G, Rezk Sandy, Li Dongzhe, Hadoux Xavier, Jannaud Maxime, Coote Michael A et al.

High-resolution microperimetry better detected glaucomatous damage than standard perimetry, suggesting its potential for earlier, more precise glaucoma diagnosis due to fundus tracking and higher sampling.

Jackson Aidan B, Martin Keith R, Coote Michael A, Medeiros Felipe A, Girkin Christopher A, Fazio Massimo A et al.

This study found 1 in 8 glaucoma eyes under routine care show fast global VF loss, and nearly 1 in 3 show significant central decline, highlighting the need for better therapies.

Nguyen Dan Q, Niyadurupola Nuwan, Tapp Robyn J, O'Connell Rachael A, Coote Michael A, Crowston Jonathan G

Phacoemulsification performed after trabeculectomy significantly increased bleb failure rates within 12 months, but not at 24 months, suggesting a short-term negative impact on glaucoma surgery success.

Niyadurupola Nuwan, Luu Chi D, Nguyen Dan Q, Geddes Kristen, Tan Gary X V, Wong Celestine C W et al.

IOP lowering in glaucoma/OHT eyes improved the PhNR amplitude, suggesting inner retinal function can recover with treatment, offering a potential marker for optic nerve health.

Chua Brian E, Nguyen Dan Q, Qin Queena, Ruddle Jonathan B, Wells Anthony P, Niyadurupola Nuwan et al.

This study found adding bevacizumab to 5-FU after trabeculectomy showed a non-significant trend toward increased bleb avascularity, but also bleb complications, warranting further safety and efficacy research.

Nguyen Dan Q, Ross Craig M, Li Yu Qin, Pandav Surinder, Gardiner Bruce, Smith David et al.

This rabbit study developed a model to measure outflow after glaucoma implant surgery, finding outflow significantly decreased by 4 weeks due to capsule thickening, clinically relevant for understanding implant failure.

Toh Tze'Yo, Nguyen Dan Q, Ruddle Jonathan B, Crowston Jonathan G, Coote Michael A

Coote Michael A, Gupta Viney, Vasudevan Sushil, Crowston Jonathan G

Posterior revision surgery for failed glaucoma blebs effectively lowers eye pressure long-term with good safety, offering a viable solution for inadequate filtration.

Toh Tze'Yo, Ruddle Jonathan B, Coote Michael A, Crowston Jonathan G

O'Neill Evelyn C, Kong Yu Xiang George, Connell Paul P, Ong Dai Ni, Haymes Sharon A, Coote Michael A et al.

Glaucoma experts exhibit systematic, pathology-focused gaze patterns during optic disc examination, unlike trainees who look longer but less efficiently. This suggests structured viewing training could improve diagnostic skills.

O'Neill Evelyn C, Danesh-Meyer Helen V, Kong George X Y, Hewitt Alex W, Coote Michael A, Mackey David A et al.

Experts struggled to differentiate ADOA and LHON from glaucoma using optic disc photos alone. This highlights the need for additional clinical data beyond disc appearance for accurate diagnosis.

Kong Yu Xiang G, Coote Michael A, O'Neill Evelyn C, Gurria Lulu U, Xie Jing, Garway-Heath David et al.

This study developed an online tool to assess optic disc examination skills, finding glaucoma subspecialists had better agreement on glaucoma likelihood and disc features than trainees, highlighting areas for skill improvement.

Ghosh Sudipta, Singh Dalveer, Ruddle Jonathan B, Shiu Michael, Coote Michael A, Crowston Jonathan G

This study found combining laser cyclophotocoagulation with intravitreal bevacizumab for neovascular glaucoma rapidly regressed neovascularization, reduced pain, and lowered eye pressure, offering a promising treatment approach.

Manni Gianluca, Denis Phillipe, Chew Paul, Sharpe Elisabeth D, Orengo-Nania Silvia, Coote Michael A et al.

This study found brinzolamide/timolol fixed combination effectively lowers IOP comparably to dorzolamide/timolol, but with significantly less ocular irritation, offering a comfort advantage for glaucoma patients.

Wilkinson Colleen H, van der Straaten David, Craig Jamie E, Coote Michael A, McCartney Paul J, Stankovich Jim et al.

Myocilin mutation carriers showed significantly reduced aqueous outflow facility, even pre-glaucoma. This suggests early detection of outflow impairment, though tonography didn't predict glaucoma progression clinically.