Gaasterland Douglas

Loomis Stephanie J, Kang Jae H, Weinreb Robert N, Yaspan Brian L, Cooke Bailey Jessica N, Gaasterland Douglas et al.

CAV1/CAV2 gene variants were studied in glaucoma patients, finding significant associations with POAG, especially in women and those with paracentral visual field loss, suggesting sex-specific disease mechanisms.

Wiggs Janey L, Hauser Michael A, Abdrabou Wael, Allingham Robert Rand, Budenz Donald L, Delbono Elizabeth et al.

The NEIGHBOR consortium was formed to standardize primary open-angle glaucoma (POAG) definitions for a large-scale genetic study, aiming to identify genes for improved diagnosis and treatment.

Pasquale Louis R, Loomis Stephanie J, Kang Jae H, Yaspan Brian L, Abdrabou Wael, Budenz Donald L et al.

CDKN2B-AS1 gene variants, linked to glaucoma risk, also influence optic nerve damage (cup-to-disc ratio) and intraocular pressure in POAG patients, highlighting its role in disease progression.

Ulmer Megan, Li Jun, Yaspan Brian L, Ozel Ayse Bilge, Richards Julia E, Moroi Sayoko E et al.

This study investigated genetic links between central corneal thickness and primary open-angle glaucoma (POAG). It found prior CCT variants weren't strongly linked to POAG, but identified new genes (NTM, CNTNAP4) associated with POAG, particularly low-tension glaucoma, suggesting potential new risk factors.

Nouri-Mahdavi Kouros, Hoffman Douglas, Gaasterland Douglas, Caprioli Joseph

This study found that early visual field "sum of slopes" and older age predict future glaucoma progression. This helps clinicians estimate worsening and guide treatment decisions.

Koucheki Behrooz, Nouri-Mahdavi Kouros, Patel Gitane, Gaasterland Douglas, Caprioli Joseph

Cataract surgery in glaucoma patients improved overall visual field sensitivity, especially in less advanced cases, but did not meaningfully change scotoma size or depth, indicating no recovery of glaucomatous damage.

Nouri-Mahdavi Kouros, Hoffman Douglas, Coleman Anne L, Liu Gang, Li Gang, Gaasterland Douglas et al.

Studying AGIS patients, researchers found older age and larger intraocular pressure (IOP) fluctuations significantly increase glaucoma visual field progression risk, highlighting IOP stability's importance.