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Ing Eliesa

7 articles in GJC

7 articles in GJC

1.

Differentiating Multiple Sclerosis and Glaucoma With Sectoral Pattern Analysis of Peripapillary Nerve Fiber Layer.

Yeh Po-Han, Tan Ou, Silbermann Elizabeth, White Elizabeth, Choi Dongseok, Chen Aiyin et al.

Transl Vis Sci TechnolNov 20240 citationsObservational Study

This study found distinct peripapillary NFL thinning patterns differentiate MS (temporal) from glaucoma (inferior/superior-temporal). Analyzing percentage reduction improves OCT's diagnostic accuracy for these optic neuropathies.

2.

Profiling IOP-Responsive Genes in the Trabecular Meshwork and Optic Nerve Head in a Rat Model of Controlled Elevation of Intraocular Pressure.

Lozano Diana C, Yang Yong-Feng, Cepurna William O, Smoody Barbara F, Ing Eliesa, Morrison John C et al.

Invest Ophthalmol Vis SciMay 20244 citationsBasic Science

This rat study found elevated IOP alters gene expression in the trabecular meshwork (TGFβ pathway downregulated) and optic nerve head (immune/defense pathways upregulated), suggesting distinct tissue responses to pressure that may impact glaucoma.

7.

Cupping in the Monkey Optic Nerve Transection Model Consists of Prelaminar Tissue Thinning in the Absence of Posterior Laminar Deformation.

Ing Eliesa, Ivers Kevin M, Yang Hongli, Gardiner Stuart K, Reynaud Juan, Cull Grant et al.

Invest Ophthalmol Vis SciMay 201616 citationsBasic Science

Monkey optic nerve transection showed cupping results from prelaminar tissue thinning, not posterior laminar deformation. This clarifies the mechanical basis of early optic nerve head changes in glaucoma.

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