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Effect of latanoprost and timolol on the histopathology of the rabbit conjunctiva.
Mietz H, Schlötzer-Schrehardt U, Strassfeld C, Krieglstein G K
Invest Ophthalmol Vis SciMar 200133 citationsBasic Science
Rabbit study found timolol increased conjunctival collagen and degenerative changes, unlike latanoprost which upregulated MMP-3. This suggests timolol-induced changes could impair glaucoma surgery outcomes.