Subramanian Prem S

Arian Roya, Behzadi Far Milad, Sadeghi Reza, Farnaghi Farshad, Safizadeh Mona, Subramanian Prem S et al.

RNFL-Net accurately segments RNFL from OCT, improving thickness measurements, especially in optic disc edema. This offers more reliable RNFL assessment for monitoring complex optic neuropathies.

Milner Dallin C, Subramanian Prem S

SANS research suggests orbital/intracranial venous pressure, not just ICP, causes eye changes in space. This is crucial for developing countermeasures for future space missions.

Vali Mahsa, Mohammadi Massood, Zarei Nasim, Samadi Melika, Atapour-Abarghouei Amir, Supakontanasan Wasu et al.

A deep learning algorithm effectively differentiated glaucomatous from non-glaucomatous optic neuropathy, outperforming specialists. This tool shows promise for accurate, automated glaucoma diagnosis.

Subramanian Prem S, Miller Neil R

Vignal-Clermont Catherine, Yu-Wai-Man Patrick, Newman Nancy J, Carelli Valerio, Moster Mark L, Biousse Valerie et al.

Lenadogene nolparvovec gene therapy for LHON showed good long-term safety. Most ocular side effects were mild, manageable inflammation/IOP, resolving with topical steroids. Systemic tolerability was excellent.

Aghsaei Fard Masoud, Salabati Mirataollah, Mahmoudzadeh Raziyeh, Kafieh Rahele, Hojati Sahar, Safizadeh Mona et al.

This study found that deep parapapillary choroidal microvasculature density is significantly reduced in glaucoma, but not ischemic optic neuropathy, suggesting its role in glaucoma's axonal damage.

Akbari Mohammadreza, Nikdel Mojgan, Moghimi Sasan, Subramanian Prem S, Fard Masoud Aghsaei

This study found superior oblique palsy eyes have thinner inferotemporal RNFL without foveal position adjustment. Correcting for disc-foveal angle (torsion) is crucial for accurate RNFL thickness assessment in these patients.

Fard Masoud Aghsaei, Sahraiyan Alireza, Jalili Jalil, Hejazi Marjane, Suwan Yanin, Ritch Robert et al.

OCT-A's whole image and nasal peripapillary capillary density can differentiate true papilledema from pseudopapilledema, offering a new diagnostic tool for optic disc swelling.

Subramanian Prem S, Gordon Lynn K, Bonelli Laura, Arnold Anthony C

Asymptomatic optic disc swelling can precede NAION vision loss by weeks. Early detection allows potential future intervention to prevent vision loss in at-risk patients.

Loo Jing-Liang, Tian Jing, Miller Neil R, Subramanian Prem S

Pre-treatment OCT's PRNFL thickness was studied in anterior visual pathway meningioma patients. Normal PRNFL predicted better post-treatment visual recovery, suggesting it helps identify patients likely to benefit from intervention.

Boland Michael V, McCoy Allison N, Quigley Harry A, Miller Neil R, Subramanian Prem S, Ramulu Pradeep Y et al.

This study developed an automated neurological hemifield test (NHT) that accurately distinguishes neurologic visual field defects from glaucoma, rivaling expert clinicians. This tool could help identify unsuspected neurologic disease.

Danesh-Meyer Helen V, Boland Michael V, Savino Peter J, Miller Neil R, Subramanian Prem S, Girkin Christopher A et al.

This study found that glaucoma eyes have distinctly different optic disc shapes (larger, deeper cups; smaller rims) than ischemic optic neuropathies, even with similar nerve damage. This helps differentiate these conditions clinically.

Donnelly Steven J, Subramanian Prem S

This study found spontaneous venous pulsations (SVP) were always present when intraocular pulse pressure (IOPP) was 1.2 mmHg or more. Absent SVP with sufficient IOPP might better predict elevated intracranial pressure.

Subramanian Prem S, Bressler Neil M, Miller Neil R

Fractionated stereotactic radiotherapy for optic nerve sheath meningioma can cause radiation retinopathy and vision loss years later, a crucial complication for patient counseling.