Yoneyama Seigo

Mabuchi Fumihiko, Tanaka-Mabuchi Nakako, Sakurada Yoichi, Yoneyama Seigo, Yamagata Zentaro, Kashiwagi Kenji

In Japanese POAG patients, genetic variants linked to high eye pressure, but not optic nerve vulnerability, predicted a history of glaucoma surgery, suggesting their role in surgical need.

Mabuchi Fumihiko, Mabuchi Nakako, Sakurada Yoichi, Yoneyama Seigo, Kashiwagi Kenji, Iijima Hiroyuki et al.

This study found non-IOP genetic variants influence POAG onset (family history), while IOP-related variants impact progression (earlier diagnosis), suggesting distinct genetic pathways for these aspects.

Mabuchi Fumihiko, Mabuchi Nakako, Takamoto Mitsuko, Sakurada Yoichi, Yoneyama Seigo, Kashiwagi Kenji et al.

A genetic variant near PLXDC2 increases primary open-angle glaucoma risk in Japanese individuals by raising intraocular pressure, highlighting a genetic predisposition for higher IOP.