Carroll A.B. Webers

Regional Comparisons of Optical Coherence Tomography Angiography Vessel Density in Primary Open-Angle Glaucoma.

Diagnostic ability of the vessel density parameters of OCTA was only moderate.

Diagnostic ability of peripapillary vessel density measurements of optical coherence tomography angiography in primary open-angle and angle-closure glaucoma.

Diagnostic ability of peripapillary vessel density parameters of OCTA, especially the inferotemporal sector measurement, was good in POAG and PACG.

XENGel Stent compared to PRESERFLO™ MicroShunt implantation for primary open-angle glaucoma: two-year results.

Xen Gel Stent and PreserFlo MicroShunt implantations achieved comparable results in POAG eyes in terms of IOP-lowering and surgical success, with a similar high safety profile.

Safety and Effectiveness of the PRESERFLO® MicroShunt in Primary Open-Angle Glaucoma: Results from a 2-Year Multicenter Study.

In this study, mean IOP and glaucoma medication reductions were significant and sustained over 2 years postsurgery. No long-term, sight-threatening AEs were reported. Further studies may confirm potential risk/benefits of higher MMC concentration.

Determinants of Peripapillary and Macular Vessel Densities Measured by Optical Coherence Tomography Angiography in Normal Eyes.

Most of the peripapillary vessel densities were higher in female subjects.

Vessel Density and Structural Measurements of Optical Coherence Tomography in Primary Angle Closure and Primary Angle Closure Glaucoma.

These results suggest that structural changes in PACG occur earlier than the reduction in retinal vessel densities.

Relationship of Optic Nerve Structure and Function to Peripapillary Vessel Density Measurements of Optical Coherence Tomography Angiography in Glaucoma.

The inferotemporal peripapillary vessel density showed the strongest association with the corresponding retinal nerve fiber layer thickness and visual sensitivity loss in the global and sectoral regions studied.

Micropulse Trans-scleral Cyclophotocoagulation in Patients With Glaucoma: 1- and 2-Year Treatment Outcomes.

Micropulse TSCPC is a safe and effective treatment for lowering both IOP and the number of IOP-lowering medications.

Choroidal Microvascular Dropout in Primary Open-angle Glaucoma Eyes With Disc Hemorrhage.

Prevalence of CMvD was significantly greater in POAG eyes with DH compared with POAG eyes without DH. CMvD in POAG eyes was also significantly associated with central VF defects and greater severity of glaucomatous damage.

Outcomes of severe uveitic glaucoma treated with Baerveldt implant: can blindness be prevented?

The BGI is an effective and safe treatment for patients with refractive secondary glaucoma due to uveitis.

Small RNA Sequencing of Aqueous Humor and Plasma in Patients With Primary Open-Angle Glaucoma.

Small RNA sequencing identified seven differentially expressed miRNAs in AH of POAG patients. The differentially expressed miRNAs may be useful as POAG biomarkers or could become targets for new therapeutic strategies.

Choroidal Microvascular Dropout in Primary Angle Closure Glaucoma.

Prevalence of CMvD was significantly lower in PACG compared to POAG. As in POAG, CMvD in PACG was associated with advanced VF damage and with IPFS on VF.

Diagnostic Abilities of the Optical Microangiography Parameters of the 3×3 mm and 6×6 mm Macular Scans in Glaucoma.

The outer sector measurements of the 6×6 mm macular OMAG scans seem to be better than the inner sector measurements in diagnosing glaucoma.

Early Phacoemulsification After Acute Angle Closure in Patients With Coexisting Cataract.

Early phacoemulsification with intraocular lens implantation results in a reduced intraocular pressure and number of glaucoma medications after an acute angle closure glaucoma crisis in patients with coexisting cataract.

A Sectoral Analysis of Vessel Density Measurements in Perimetrically Intact Regions of Glaucomatous Eyes: An Optical Coherence Tomography Angiography Study.

Within the perimetrically intact regions of glaucomatous eyes, the mean VD and RNFL thickness were significantly reduced in inferotemporal, superonasal, and nasal upper peripapillary sectors as compared with healthy eyes (P<0.008).

Optical Coherence Tomography Angiography Vessel Density Measurements in Eyes With Primary Open-Angle Glaucoma and Disc Hemorrhage.

OCT angiography measured vessel densities and their diagnostic abilities in POAG eyes with and without DH were similar. This suggests that the cause of DH in POAG is unlikely to be vascular abnormality.

Choroidal Microvascular Dropout in Pseudoexfoliation Glaucoma.

The prevalence of CMvD was significantly lower in the PXG eyes when compared with the POAG eyes.

Comprehensive bioinformatics analysis of trabecular meshwork gene expression data to unravel the molecular pathogenesis of primary open-angle glaucoma.

This study provides an overview of the processes involved in the molecular pathogenesis of POAG in the TM.

Risk Factors for the Development of Ocular Hypertension After Keratoplasty: A Systematic Review.

Risk factors with a definite association can help clinicians select patients at risk and adjust their follow-up and treatment. The other factors need further investigation.

Diagnostic Ability and Structure-function Relationship of Peripapillary Optical Microangiography Measurements in Glaucoma.

The inferior sector OMAG measurements had the best diagnostic ability in glaucoma and the strongest association with RNFL and the visual sensitivity measurements.

Optical Coherence Tomography Angiography and Visual Field Progression in Primary Angle Closure Glaucoma.

Lower superficial vessel density measured using OCTA was significantly associated with faster VF progression in PACG. In these eyes, OCTA parameters can serve as biomarker suggestive of past VF progression.

Relationship of Macular Thickness and Function to Optical Microangiography Measurements in Glaucoma.

The strongest associations between OMAG, GCIPL thickness, and visual sensitivity measurements were found in the inferior macular sector.

Intraocular Pressure Fluctuations and 24-Hour Continuous Monitoring for Glaucoma Risk in Wind Instrument Players.

IOP often rises after playing wind instruments, but similar or even higher IOP levels seem to occur during common other daily activities or at night.

Optical Microangiography and Progressive Retinal Nerve Fiber Layer Loss in Primary Open Angle Glaucoma.

Lower baseline peripapillary PD and VD measured using OMAG were significantly associated with a faster rate of RNFL loss in POAG.

Five-year follow-up with the PreserFlo MicroShunt for open-angle glaucoma.

After five years, the MicroShunt was found to be a safe procedure, leading to a sustained reduction in mean IOP and number of IOP-lowering medications.

Progressive Vessel Density Reduction on OCT Angiography in Glaucoma Eyes with Disc Hemorrhages.

Eyes with POAG harboring a DH showed not only progressive RNFL and GCIPL loss in the DH sector, but also progressive peripapillary and parafoveal VD reduction in the DH and non-DH regions as documented on…

Does the Presence of a Disc Hemorrhage Affect OCT-Measured Vessel Density and Retinal Nerve Fiber Layer Thickness?

The presence of a DH does not artifactually alter the VD or RNFL thickness measurements. Therefore, OCT scans obtained in the presence of a DH may be included in series used for studying progression.

Optical Microangiography and Progressive Ganglion Cell-Inner Plexiform Layer Loss in Primary Open-Angle Glaucoma.

Lower baseline peripapillary OMAG measurements were significantly associated with a faster rate of GCIPL loss in patients with mild to moderate POAG.

Upregulated NOTCH Signaling in the Lens of Patients With Pseudoexfoliation Syndrome Compared With Pseudoexfoliation Glaucoma Suggests Protective Role.

The finding that NOTCH signaling is significantly upregulated in the lens capsule of eyes with PXF and not in PXG or POAG patients suggests a possible protective role in the development of glaucoma.

Circulating eNAMPT in Glaucoma: A Semi-Quantitative Plasma Analysis Before and After Nicotinamide Supplementation.

eNAMPT is readily and specifically detected by Western blotting in plasma from healthy controls and patients with glaucoma.

Optical Microangiography and Progressive Retinal Nerve Fiber Layer Loss in Primary Angle Closure Glaucoma.

Younger patient age and greater peak IOP during follow-up were significantly associated with a faster rate of RNFL loss in PACG patients with mild to moderate severity of functional damage.

Response to Letter to the Editor: Optical Coherence Tomography Angiography and Visual Field Progression in Primary Angle Closure Glaucoma.

Corneal endothelial cell loss after Baerveldt glaucoma drainage device implantation in the anterior chamber.

The TC distance is of significant influence on corneal ECD, a shorter TC distance causing more severe EC loss, especially in the PQC.

A Systematic Review of End-of-Life Visual Impairment in Open-Angle Glaucoma: An Epidemiological Autopsy.

CONCLUSIONS: Further prevention of blindness in glaucoma patients is needed.

Prediction of Glaucomatous Visual Field Progression Using Baseline Clinical Data.

Although our prediction model could explain only a small amount of the variance in visual field progression, it may offer the possibility to identify subgroups of treated patients with high rates of visual field progression,…

Ocular hypertension and the risk of blindness.

The best estimates of the 15-year risk of unilateral blindness in patients with OHT, based on the currently available empirical data and an appropriate model, show that the risk is <10%.