Global Search

Search articles, concepts, and chapters

Clin Exp OphthalmolMay 201621 citations

Factors affecting refractive outcome after cataract surgery in primary angle-closure glaucoma.

Seo Sam, Lee Chong Eun, Kim Young Kook, Lee Sang Yoon, Jeoung Jin Wook, Park Ki Ho


AI Summary

This study found IOL power predictions in PAC/PACG cataract surgery are often hyperopic. Relative lens vault was a key predictor of refractive error, suggesting its importance for improving accuracy in these complex cases.

Abstract

Background

To evaluate the biometric factors associated with the accuracy of intraocular lens power predictions for cataract surgery in primary angle-closure (PAC) or primary angle-closure glaucoma (PACG) eyes.

Design

Cross-sectional study PARTICIPANTS: This study included 103 PAC or PACG patients who had undergone cataract surgery.

Methods

All participants underwent anterior-segment optical coherence tomography preoperatively. Two novel biometric factors - the relative lens vault (the ratio of lens vault to anterior vault) and the anterior vault (the sum of lens vault and anterior chamber depth) - were measured using customized software. The powers of the implanted intraocular lens and the actual postoperative refractive errors were compared. The mean refractive error and the median absolute error were calculated and compared using repeated measures ANOVA and Wilcoxon matched-pairs signed-rank test. The biometric factors associated with the postoperative refractive error were investigated by multivariate regression analysis.

Main outcome measures

Preoperative anterior-segment biometric factors, difference between predicted and actual postoperative refraction.

Results

The Haigis, Hoffer Q and SRK/T formulas all showed a slight tendency toward resultant hyperopia, respectively (P < 0.001, P = 0.05, P = 0.003). The Hoffer Q formula had the least prediction error (P < 0.001). In the multivariate regression analysis, the relative lens vault was the only independent factor predicting postoperative refractive error (β = 0.392, P = 0.011).

Conclusion

Intraocular lens power predictions for cataract surgery in PAC or PACG patients can be inaccurate. Such results might be associated with anterior-segment biometric factors. Preoperative relative lens vault appears to be a significant factor predicting refractive outcome after cataract surgery in patients with PAC or PACG.


MeSH Terms

AgedAnterior Eye SegmentBiometryFemaleGlaucoma, Angle-ClosureHumansLens Implantation, IntraocularLenses, IntraocularMaleMiddle AgedOptics and PhotonicsPhacoemulsificationPseudophakiaRefraction, OcularRetrospective StudiesTomography, Optical CoherenceVisual Acuity

Key Concepts4

The Haigis, Hoffer Q, and SRK/T formulas for intraocular lens power prediction in cataract surgery for primary angle-closure (PAC) or primary angle-closure glaucoma (PACG) eyes all showed a slight tendency toward resultant hyperopia (P < 0.001, P = 0.05, P = 0.003, respectively).

PrognosisCross-sectionalCross-sectional studyn=103 PAC or PACG patientsCh13Ch19Ch44

The Hoffer Q formula had the least prediction error among the Haigis, Hoffer Q, and SRK/T formulas for intraocular lens power prediction in cataract surgery for primary angle-closure (PAC) or primary angle-closure glaucoma (PACG) eyes (P < 0.001).

Comparative EffectivenessCross-sectionalCross-sectional studyn=103 PAC or PACG patientsCh13Ch19Ch44

The relative lens vault was the only independent factor predicting postoperative refractive error after cataract surgery in primary angle-closure (PAC) or primary angle-closure glaucoma (PACG) patients (β = 0.392, P = 0.011).

PrognosisCross-sectionalCross-sectional studyn=103 PAC or PACG patientsCh13Ch19Ch44

Intraocular lens power predictions for cataract surgery in primary angle-closure (PAC) or primary angle-closure glaucoma (PACG) patients can be inaccurate, and these inaccuracies might be associated with anterior-segment biometric factors.

PrognosisCross-sectionalCross-sectional studyn=103 PAC or PACG patientsCh13Ch19Ch44

Is this article assigned to the wrong chapter(s)? Let us know.