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Long-term in vivo imaging and measurement of dendritic shrinkage of retinal ganglion cells.
Leung Christopher Kai-shun, Weinreb Robert N, Li Zhi Wei, Liu Shu, Lindsey James D, Choi Nathan et al.
Invest Ophthalmol Vis SciMar 201198 citationsBasic Science
This study found that retinal ganglion cell (RGC) dendritic shrinkage precedes axon/cell body loss in mice after optic nerve crush. Larger dendrites predicted better RGC survival, suggesting a new way to track glaucoma progression and treatment efficacy.