Leung Christopher Kai-shun

Yang Bingzhi, Ye Cong, Yu Marco, Liu Shu, Lam Dennis Shun Chiu, Leung Christopher Kai-shun

This study found OCT and HRT optic disc measurements poorly agree, with OCT measuring smaller discs/rims. However, both instruments show high reproducibility, suggesting OCT may offer more precise monitoring.

Liu Shu, Li Zhi-wai, Weinreb Robert N, Xu Guihua, Lindsey James D, Ye Cong et al.

This study tracked retinal microglia in mice after optic nerve injury, finding microgliosis correlates with RGC loss. This imaging method could help assess glaucoma progression and treatment efficacy.

Xu Guihua, Lam Dennis Shun, Leung Christopher Kai-shun

This study found higher ocular pulse amplitude increases variability in ORA-measured IOP, but not corneal biomechanics. Clinically, this means averaging multiple ORA readings is crucial, especially in eyes with large pulse amplitudes.

Leung Christopher Kai-shun, Weinreb Robert N, Li Zhi Wei, Liu Shu, Lindsey James D, Choi Nathan et al.

This study found that retinal ganglion cell (RGC) dendritic shrinkage precedes axon/cell body loss in mice after optic nerve crush. Larger dendrites predicted better RGC survival, suggesting a new way to track glaucoma progression and treatment efficacy.

Leung Christopher Kai-shun, Ye Cong, Weinreb Robert N, Cheung Carol Yim Lui, Qiu Quanliang, Liu Shu et al.

This study found Spectralis OCT retinal nerve fiber layer imaging had higher sensitivity than HRT optic disc measurements for glaucoma detection, suggesting superior diagnostic performance.

Leung Christopher Kai-shun, Cheung Carol Yim Lui, Weinreb Robert N, Qiu Kunliang, Liu Shu, Li Haitao et al.

This study showed OCT RNFL thinning rates vary in glaucoma, with faster loss in eyes having thicker baseline RNFL, aiding progression analysis.

Leung Christopher Kai-shun, Lindsey James D, Crowston Jonathan G, Lijia Chen, Chiang Sylvia, Weinreb Robert N

Using bCSLO, researchers found optic nerve crush causes rapid, then slower, progressive RGC loss in mice, highlighting a non-invasive tool for studying glaucoma progression.

Leung Christopher Kai-shun, Cheung Carol Yim-lui, Lin Dusheng, Pang Chi Pui, Lam Dennis S C, Weinreb Robert N

This study found that OCT, SLP, and CSLO measurements of optic disc and RNFL have low variability, making them reliable tools for monitoring glaucoma progression regardless of disease severity.

Leung Christopher Kai-shun, Li Haitao, Weinreb Robert Neal, Liu Jing, Cheung Carol Yim Lui, Lai Ricky Yiu Kwong et al.

This study compared two OCT devices (Visante, SLOCT) for anterior chamber angle measurements. Both showed good interobserver reproducibility, but their agreement with each other was poor, impacting interchangeable clinical use.

Leung Christopher Kai-shun, Cheung Carol Yim Lui, Li Haitao, Dorairaj Syril, Yiu Cedric Ka Fai, Wong Amy Lee et al.

AS-OCT revealed that anterior chamber angles generally narrow in the dark, but the degree of change varies widely among individuals, correlating with anterior chamber depth. This highlights personalized angle closure risk.

Leung Christopher Kai-shun, Medeiros Felipe A, Zangwill Linda M, Sample Pamela A, Bowd Christopher, Ng Diana et al.

This study found retinal nerve fiber layer (RNFL) measurements are superior to neuroretinal rim measurements for detecting glaucoma and correlating with visual function, guiding better diagnostic choices.

Leung Christopher Kai-shun, Yick Doris Wai-fong, Kwong Yolanda Yuen-ying, Li Felix Chi-hong, Leung Dexter Yu-lung, Mohamed Shaheeda et al.

Visante OCT effectively characterized diverse post-trabeculectomy bleb morphologies, linking internal structures to function and slit-lamp appearance, which can inform surgical outcomes and wound healing studies.

Leung Christopher Kai-shun, Chong Kelvin Kam-Long, Chan Wai-man, Yiu Cedric Ka-Fai, Tso Man-yee, Woo Jackson et al.

This study compared StratusOCT and GDx VCC for assessing glaucoma's structure/function relationship. StratusOCT RNFL measurements showed stronger associations with visual function, suggesting it's a better tool for clinical evaluation.

Leung Christopher Kai-shun, Chan Wai-man, Chong Kelvin Kam-Long, Yung Wing-ho, Tang Kai-tat, Woo Jackson et al.

This study compared StratusOCT and GDx VCC for measuring retinal nerve fiber layer in glaucoma. Despite different absolute values, measurements correlated well, and both devices effectively detected glaucoma.

Leung Christopher Kai-shun, Chan Wai-Man, Hui Yung-Lam, Yung Wing-Ho, Woo Jackson, Tsang Moon-Kwong et al.

OCT analysis of RNFL and ONH using a 150µm reference plane best detected early glaucoma and correlated with visual function, improving diagnostic accuracy.