Herndon Leon W

Choi Eun Young, Johnson Nicholas A, Stinnett Sandra, Rosdahl Jullia, Moya Frank, Herndon Leon W

This study found bimatoprost implants significantly reduced the need for topical glaucoma drops for up to a year, particularly in mild to moderate disease, offering a potential treatment burden reduction.

Jackson Kevin J, Akrobetu Dennis, Guduru Abhilash, Herndon Leon W

This study found that an intracanalicular dexamethasone insert and topical prednisolone provided similar short-term control of inflammation after iStent/Hydrus surgery, offering a potential alternative to drops.

Birnbaum Faith A, Mirzania Delaram, Swaminathan Swarup S, Davis Andrew R, Perez Victor L, Herndon Leon W

This study found corneal striae after glaucoma surgery linked to steeper corneas, induced astigmatism, and higher corneal hysteresis, suggesting these factors impact corneal deformation at low pressures and are clinically relevant for visual outcomes.

Mwanza Jean-Claude, Tulenko Samantha E, Budenz Donald L, Herndon Leon W, Hall Alyson, Hay-Smith Graham et al.

This study found high rates of glaucoma progression (9.7%/year) and visual field deterioration (-1.02 dB/year) in urban Ghanaians, highlighting the aggressive nature of the disease in this population.

Swaminathan Swarup S, Quist Michael S, Dawson Lindsay E, Rothman Adam L, Herndon Leon W

Nylon wicks with fenestrations in nonvalved aqueous shunts significantly lowered early postoperative IOP and medication use, offering better pressure control while awaiting ligature dissolution.

Bargoud Albert R, Lira Jennifer, An Selena, Walsman Scott M, Herndon Leon W, Khouri Albert S

iStent/phacoemulsification effectively lowered eye pressure and medication use for African American glaucoma patients, even with prior laser, offering a safe treatment option.

Nwanaji-Enwerem Jamaji C, Wang Weiye, Nwanaji-Enwerem Onyemaechi, Vokonas Pantel, Baccarelli Andrea, Weisskopf Marc et al.

Long-term black carbon exposure was linked to higher intraocular pressure in older men with high oxidative stress genetic susceptibility, suggesting air pollution may increase glaucoma risk in vulnerable individuals.

An Selena J, Wen Joanne C, Quist Michael S, Mathenge Elizabeth W, Vin Anita, Herndon Leon W

Scheduled ripcord removal in Baerveldt 350 implants showed similar IOP and success, but reduced medication burden and tube obstruction, potentially improving patient quality of life.

Rothman Adam L, An Selena J, Herndon Leon W

Studying Baerveldt 350 surgery, a vicryl suture wick offered no additional early IOP control or complication benefits over standard fenestration, suggesting limited clinical utility for this technique.

Mwanza Jean-Claude, Tulenko Samantha E, Barton Keith, Herndon Leon W, Mathenge Elizabeth, Hall Alyson et al.

This Ghanaian study found an 8-year OAG incidence of 4.6%, higher than non-Black populations. Key risks included male gender, older age, higher IOP, larger cup-to-disc ratio, and thinner corneas, highlighting the need for targeted screening.

Quist Michael S, Brown Ninita, Bicket Amanda K, Herndon Leon W

This study compared MMC application methods in trabeculectomy, finding irrigation provided better short-term IOP control and reduced reoperations versus sponges, despite more hypotony, suggesting improved outcomes.

Yuan Fan, Schieber Andrew T, Camras Lucinda J, Harasymowycz Paul J, Herndon Leon W, Allingham R Rand

Mathematical modeling showed glaucoma devices bypassing the trabecular meshwork and dilating Schlemm's canal significantly increase outflow facility, with longer dilation leading to greater improvement, impacting clinical efficacy.

Prum Bruce E, Rosenberg Lisa F, Gedde Steven J, Mansberger Steven L, Stein Joshua D, Moroi Sayoko E et al.

These updated guidelines provide evidence-based recommendations and an algorithm for diagnosing and managing primary open-angle glaucoma, offering clinicians clear guidance on patient evaluation and treatment options.

Prum Bruce E, Herndon Leon W, Moroi Sayoko E, Mansberger Steven L, Stein Joshua D, Lim Michele C et al.

These updated guidelines provide evidence-based recommendations for diagnosing and managing primary angle closure, offering clinicians detailed options for patient evaluation and treatment.

Prum Bruce E, Lim Michele C, Mansberger Steven L, Stein Joshua D, Moroi Sayoko E, Gedde Steven J et al.

These updated guidelines provide evidence-based recommendations for diagnosing and managing primary open-angle glaucoma suspects, offering clinicians clear guidance for patient care.

Liu Yutao, Hauser Michael A, Akafo Stephen K, Qin Xuejun, Miura Shiroh, Gibson Jason R et al.

Studying POAG genetics in African Americans and Ghanaians, researchers found Caucasian-associated risk factors play a reduced role, underscoring the need for new genetic studies in these high-risk populations.

Gedde Steven J, Herndon Leon W, Brandt James D, Budenz Donald L, Feuer William J, Schiffman Joyce C

This study compared complications of tube shunts vs. trabeculectomy for glaucoma. Trabeculectomy had more early complications, but late complications and reoperations were similar over five years, guiding surgical choice.

Gedde Steven J, Schiffman Joyce C, Feuer William J, Herndon Leon W, Brandt James D, Budenz Donald L

The TVT study found tube shunts had higher 5-year success and fewer reoperations than trabeculectomy with MMC for complex glaucoma, despite similar IOP control, suggesting tubes are a more durable option.

Tanna Angelo P, Budenz Donald L, Bandi Jagadeesh, Feuer William J, Feldman Robert M, Herndon Leon W et al.

This study compared GPA software with expert consensus for detecting glaucoma visual field progression. It found fair agreement, with experts more often identifying progression than the software, highlighting the value of clinical judgment.

Tanna Angelo P, Bandi Jagadeesh R, Budenz Donald L, Feuer William J, Feldman Robert M, Herndon Leon W et al.

Glaucoma experts showed good intraobserver visual field progression reproducibility, but only moderate interobserver agreement, which GPA data did not improve, highlighting subjective interpretation challenges.

Malone Paula E, Herndon Leon W, Muir Kelly W, Jaffe Glenn J

Combined fluocinolone acetonide implant and glaucoma drainage device for uveitic glaucoma was safe and effective, reducing inflammation, improving vision, and lowering IOP. This offers a single-session treatment option.

Gedde Steven J, Schiffman Joyce C, Feuer William J, Budenz Donald L, Herndon Leon W, Brandt James D

Gedde Steven J, Schiffman Joyce C, Feuer William J, Herndon Leon W, Brandt James D, Budenz Donald L

The TVT study found tube shunts had a higher 3-year success rate and fewer complications than trabeculectomy with MMC for uncontrolled glaucoma, despite similar IOP control, making tubes a favorable option.

Stein Joshua D, McCoy Allison N, Asrani Sanjay, Herndon Leon W, Lee Paul P, McKinnon Stuart J et al.

Overfiltration causing hypotony after glaucoma drainage device surgery is rare (1.6%). Prolene suture ligation was more effective than polyglactin for surgical revision, improving patient outcomes.

Duarte Maria C, Herndon Leon W, Gupta Preeya K, Afshari Natalie A