Tatham Andrew J

Kolko Miriam, Tatham Andrew J, Lim Kin Sheng, Wells Anthony P, Shiu Michael, Uy Harvey S et al.

This study found the bimatoprost implant noninferior to SLT for lowering IOP in glaucoma patients. Both offered sustained IOP reduction, with flexible implant retreatment improving safety, providing alternative treatment options.

Katsimpris Andreas, Baumeister Sebastian-Edgar, Baurecht Hansjörg, Tatham Andrew J, Nolde Michael

This Mendelian randomization study found higher central corneal thickness is associated with an increased primary open-angle glaucoma risk, with 28.4% mediated by intraocular pressure. This contradicts prior observational findings.

Azuara-Blanco Augusto, McCorry Noleen, Tatham Andrew J, Georgoulas Stelios, Founti Panayiota, Schweitzer Cedric et al.

European stakeholders identified top glaucoma research priorities: treatments to restore vision/stop sight loss and improved detection of worsening. This guides future research and investment.

Olyntho Marco A C, Jorge Carlos A C, Castanha Everton B, Gonçalves Andreia N, Silva Barbara L, Nogueira Bernardo V et al.

Deep learning on AS-OCT accurately detects angle closure (94% sensitivity/93.6% specificity), offering a promising screening tool, especially where ophthalmologists or gonioscopy are scarce.

Gibbon Samuel, Muniz-Terrera Graciela, Yii Fabian S L, Hamid Charlene, Cox Simon, Maccormick Ian J C et al.

This study developed software quantifying optic disc pallor from fundus photos. It found pallor correlated with thinner retinal nerve fiber layer, offering a robust tool for identifying and monitoring optic neuropathies like glaucoma.

Dhillon Seth, Deol Sundeep, Tatham Andrew J

Wong Thai Ling, Ang Juan Lyn, Deol Sundeep, Buckmaster Fiona, McTrusty Alice D, Tatham Andrew J

This study found higher socioeconomic deprivation is significantly associated with more severe glaucoma at diagnosis, indicating a critical health inequality needing targeted intervention to prevent advanced disease.

Barbour-Hastie Catriona, Deol Sundeep S, Peroni Andrea, Gillan Stewart, Trucco Emanuele, Tatham Andrew J

Automated gonioscopy provided good angle images, was well-tolerated, and preferred by patients. This suggests a feasible, comfortable alternative to traditional gonioscopy for glaucoma assessment.

Cheng Kelvin K W, Young Su Ling, Donaldson Sarah, Malcolm Tej Rene, Tatham Andrew J

Virtual glaucoma clinic patients showed surprisingly high medication adherence (91%), especially those self-instilling drops. This suggests virtual care can be effective, but education remains crucial.

Barbour-Hastie Catriona C, Tatham Andrew J

Remote video teaching for home tonometry was feasible and successful for most glaucoma patients, offering a convenient way to monitor IOP.

Saxby Edward, Mansouri Kaweh, Tatham Andrew J

An implanted sensor remotely monitored a patient's IOP, guiding timely glaucoma surgery and confirming post-operative control, demonstrating its value for managing this condition.

Ali Ameer M, O'Connell Niamh M, Tatham Andrew J

Tatham Andrew J, Ali Ameer M, Hillier Niamh

This study found glaucoma knowledge is similar in virtual and in-person clinic patients, but significant gaps exist in both groups, highlighting the need for enhanced patient education in all glaucoma services.

Tan Boo Hui, Young Alexandra, Bianchi Eleonora, Brown Lyndsay, Tatham Andrew J

This study found normal tension glaucoma patients often exhibit vascular dysregulation, including hypertension, blunted nocturnal blood pressure dipping, and morning blood pressure surge, highlighting systemic factors in disease.

Ikeda Mariana C, Bando Andre H, Hamada Koiti U, Nakamura Vinicius P L, Prata Tiago S, Paranhos Augusto et al.

Glaucoma patients with preserved central vision showed significantly slower reading speeds than controls. This highlights that even mild glaucoma can impair daily tasks like reading, impacting quality of life.

Perperidis Antonios, McTrusty Alice D, Cameron Lorraine A, Murray Ian C, Brash Harry M, Fleck Brian W et al.

Modified SVOP successfully assessed visual fields in most healthy infants. This eye-tracking perimetry shows promise for automated, objective infant visual field assessment, potentially improving early glaucoma detection.

Tatham Andrew J, McClean Pam, Murray Ian C, McTrusty Alice D, Cameron Lorraine A, Perperidis Antonios et al.

This study developed age-corrected normal values for a new eye-tracking perimeter (SVOP). SVOP showed higher, but not interchangeable, sensitivities compared to standard perimetry, with similar age-related decline.

Young Su Ling, Smith Margaret L, Tatham Andrew J

Poorly fitted face masks during visual field testing can cause artifacts mimicking glaucoma, even with good reliability. Clinicians must ensure proper mask fit to prevent misdiagnosis.

Mostafa Islam, Bianchi Eleonora, Brown Lyndsay, Tatham Andrew J

This study found ORA provided more reliable and repeatable IOP measurements than nurse-performed GAT, suggesting it's a better tool for virtual glaucoma clinics.

Hogan Brian, Trew Chris, Annoh Roxanne, Yi Loo Cheng, Ling Tan Huai, Shan Tang Ling et al.

Studying disc hemorrhages (DHs) for glaucoma, researchers found DHs alone had a 24% positive predictive value for open-angle glaucoma and a 57% discharge rate, while DHs plus other signs strongly indicated glaucoma.

Rotchford Alan P, Hughes John, Agarwal Pankaj Kumar, Tatham Andrew J

Scottish glaucoma medication use increased 27% (2010-2017), more than double expected from population aging alone, suggesting broader diagnostic or treatment changes.

Hughes Laura, Loo Cheng Yi, Hogan Brian, Tan Huai Ling, Tang Ling Shan, Tatham Andrew J

This study found community optometrists' CCT measurements largely agree with glaucoma clinic readings, though slightly thicker, suggesting their CCT data is generally reliable for glaucoma risk assessment.

Brown Lyndsay, Foulsham William, Pronin Savva, Tatham Andrew J

This study found self-tonometer IOPs, like GAT, are significantly influenced by overall corneal biomechanics (CH/CRF), not just CCT, impacting home monitoring accuracy.

Zhang Chunwei, Tatham Andrew J, Daga Fábio B, Jammal Alessandro A, Medeiros Felipe A

This study found visual field GPA often misses rapid glaucoma progression detected by a combined structural and functional index, highlighting the need for comprehensive monitoring.

Bo Jenny, Changulani Tulsi, Cheng Mei-Ling, Tatham Andrew J

LPI for angle closure often leads to lens extraction, especially with older age and higher initial IOP. Early lens extraction may be considered for these patients.