De Moraes C Gustavo

Wang Qing, Valenzuela Ives A, Harizman Noga, Gorroochurn Prakash, Torres Desiree R, Maruri Stefania C et al.

Community-based glaucoma screening in high-risk populations effectively identified many needing further evaluation. This supports targeted public health screenings to detect glaucoma early in underserved communities.

KhalafAllah Mahmoud T, Zangwill Linda M, Proudfoot James, Walker Evan, Girkin Christopher A, Fazio Massimo A et al.

OCT RNFLT diagnostic accuracy for glaucoma is lower in individuals of African descent than European descent, highlighting racial differences impacting clinical interpretation.

Kastner Alan, Stuart Kelsey V, Montesano Giovanni, De Moraes C Gustavo, Kang Jae H, Wiggs Janey L et al.

This study found calcium channel blocker use linked to 39% higher glaucoma odds and thinner retinal nerve layers, suggesting an IOP-independent neurodegenerative mechanism.

Melchior Bruna, De Moraes C Gustavo, Paula Jayter S, Cioffi George A, Gordon Mae O, Kass Michael A et al.

This study found that 6-month visual field testing optimally detects glaucoma progression in high-risk ocular hypertension, while 12-month intervals suffice for low-risk patients, balancing detection with resource use.

Villasana Gabriel A, Bradley Chris, Elze Tobias, Myers Jonathan S, Pasquale Louis, De Moraes C Gustavo et al.

This study found that including and correcting for unreliable visual fields significantly improves glaucoma progression forecasting accuracy, potentially enabling earlier detection of worsening.

Zemborain Zane Z, Tsamis Emmanouil, La Bruna Sol, Leshno Ari, De Moraes C Gustavo, Ritch Robert et al.

This study found a novel OCT metric (RMS cpRNFL) best distinguished healthy from glaucomatous eyes with low nerve fiber layer thickness, achieving 90% accuracy, improving diagnosis in challenging cases.

Melchior Bruna, Valenzuela Ives A, De Moraes C Gustavo, Paula Jayter S, Fazio Massimo A, Girkin Christopher A et al.

This 11-year study found similar glaucoma visual field progression rates between Black and White patients in a referral setting, suggesting equitable care may reduce previously observed racial disparities.

Leshno Ari, De Moraes C Gustavo, Mezad-Koursh Daphna, Belkin Michael, Singer Reut, Jaber Wasim et al.

Glaucoma publications increased in experimental journals but decreased for randomized clinical trials over 25 years, suggesting a shift from clinical validation to basic research, potentially due to funding changes.

Eguia Melvi D, Tsamis Emmanouil, Zemborain Zane Z, Sun Ashley, Percival Joseph, De Moraes C Gustavo et al.

Global circumpapillary RNFL thickness poorly detects glaucoma progression due to local defects and segmentation errors. Clinically, relying solely on this metric is unreliable; image review is crucial.

Kim Ha Min, McKee William E, Malendowicz Katarzyna B, Thenappan Abinaya A, Tsamis Emmanouil, Eguia Melvi D et al.

OCT showed glaucoma progression involves cRNFL widening and deepening, but patterns vary greatly. This means visual field changes will also vary, and standard metrics may miss crucial progression details.

Hood Donald C, Thenappan Abinaya A, Tsamis Emmanouil, Liebmann Jeffrey M, De Moraes C Gustavo

This study found that new 24-2 and 10-2 visual field metrics often miss early central glaucoma damage. A topographic approach combining OCT and 10-2 visual fields is recommended for better detection.

Shukla Aakriti G, De Moraes C Gustavo, Cioffi George A, Girkin Christopher A, Weinreb Robert N, Zangwill Linda M et al.

This study found IOP parameters similarly impact central and peripheral visual field progression in glaucoma, suggesting IOP control benefits both regions equally.

Shukla Aakriti G, Sirinek Portia E, De Moraes C Gustavo, Blumberg Dana M, Cioffi George A, Skaat Alon et al.

Disc hemorrhages in glaucoma are linked to more severe central visual field damage and faster progression, emphasizing the need for intensive central VF monitoring.

Garg Aakriti, De Moraes C Gustavo, Cioffi George A, Girkin Christopher A, Medeiros Felipe A, Weinreb Robert N et al.

Baseline central visual field damage in glaucoma predicts faster overall vision loss, indicating these patients need intensive monitoring and treatment.

Prager Alisa J, Hood Donald C, Liebmann Jeffrey M, De Moraes C Gustavo, Al-Aswad Lama A, Yu Qi et al.

This study found that diffuse macular damage in glaucoma patients, identified by OCT, is a stronger predictor of worse vision-related quality of life than simple thickness measurements, guiding personalized care.

De Moraes C Gustavo, Murphy James T, Kaplan Chad M, Reimann Jeremy J, Skaat Alon, Blumberg Dana M et al.

This study found that baseline βPPA was linked to faster visual field progression in European descent glaucoma patients, but not African descent. βPPA progression itself didn't predict faster visual field loss.

De Moraes C Gustavo, Hood Donald C, Thenappan Abinaya, Girkin Christopher A, Medeiros Felipe A, Weinreb Robert N et al.

This study found 24-2 visual fields often miss central defects detected by 10-2 tests in glaucoma suspects, ocular hypertensives, and early glaucoma, impacting diagnosis and severity classification.

De Moraes C Gustavo, Liebmann Jeffrey M, Levin Leonard A

This paper argues a 30% reduction in glaucoma visual field progression rate over 12-18 months is clinically meaningful, impacting quality of life. This helps define trial endpoints beyond IOP.

Blumberg Dana M, Prager Alisa J, Liebmann Jeffrey M, Cioffi George A, De Moraes C Gustavo

Medicare Part D reduced cost-related glaucoma medication skipping/dose reduction and cost-saving behaviors. However, failure to fill prescriptions due to cost remained stable, highlighting ongoing financial barriers for some patients.

Kaplan Richard I, De Moraes C Gustavo, Cioffi George A, Al-Aswad Lama A, Blumberg Dana M

This study found trabeculectomy and tube implants are cost-effective versus medical glaucoma treatment, but trabeculectomy offers better value per quality-adjusted life-year gained.

Babic Mirko, De Moraes C Gustavo, Hatanaka Marcelo, Ju Guilherme, Susanna Remo

This study found water drinking test IOP peaks are highly reproducible in treated glaucoma patients, making it useful for assessing treatment efficacy, unlike IOP fluctuation.