Leite Mauro T

Gracitelli Carolina P B, Moreno Pilar A, Leite Mauro T, Prata Tiago S

This study found peripapillary retinal nerve fiber layer (pRNFL) thickness is significantly thinner in early low-tension glaucoma (LTG) than high-tension glaucoma (HTG), and more accurate for diagnosing LTG.

Lisboa Renato, Paranhos Augusto, Weinreb Robert N, Zangwill Linda M, Leite Mauro T, Medeiros Felipe A

SDOCT retinal nerve fiber layer measurements best detected preperimetric glaucoma in suspects, outperforming ONH and macular scans. This highlights RNFL's value for early diagnosis.

Moore Grant H, Bowd Christopher, Medeiros Felipe A, Sample Pamela A, Liebmann Jeffrey M, Girkin Christopher A et al.

This study found healthy individuals of African descent have greater optic disc asymmetry than European descent, but this difference disappears after accounting for disc size. Defining normal asymmetry ranges helps identify glaucoma suspects.

Lisboa Renato, Leite Mauro T, Zangwill Linda M, Tafreshi Ali, Weinreb Robert N, Medeiros Felipe A

SD-OCT retinal nerve fiber layer analysis effectively detects preperimetric glaucoma, outperforming CSLO. This improves early diagnosis, allowing earlier intervention to preserve vision.

Mansouri Kaweh, Leite Mauro T, Weinreb Robert N, Tafreshi Ali, Zangwill Linda M, Medeiros Felipe A

This study found corneal biomechanics (CH, CRF) had only a weak association with glaucoma severity (visual field, RNFL thickness), suggesting limited clinical utility for assessing disease progression.

Leite Mauro T, Zangwill Linda M, Weinreb Robert N, Rao Harsha L, Alencar Luciana M, Medeiros Felipe A

This study found a strong link between OCT-measured nerve fiber layer thinning and corresponding visual field loss in glaucoma, especially in specific sectors, validating OCT's role in detecting structural damage.

Mansouri Kaweh, Leite Mauro T, Weinreb Robert N

Leite Mauro T, Rao Harsha L, Zangwill Linda M, Weinreb Robert N, Medeiros Felipe A

This study compared three OCT devices for glaucoma detection. All showed similar diagnostic accuracy for retinal nerve fiber layer thickness, implying comparable clinical utility despite technical differences.

Medeiros Felipe A, Leite Mauro T, Zangwill Linda M, Weinreb Robert N

This study found a Bayesian model combining structural and functional tests significantly improved glaucoma progression detection compared to standard methods, offering better clinical monitoring.

Rao Harsha L, Leite Mauro T, Weinreb Robert N, Zangwill Linda M, Alencar Luciana M, Sample Pamela A et al.

RTVue SDOCT glaucoma diagnosis improves with disease severity, but optic disc size doesn't impact overall accuracy. Larger discs increase rim area sensitivity but reduce specificity.

Leite Mauro T, Rao Harsha L, Weinreb Robert N, Zangwill Linda M, Bowd Christopher, Sample Pamela A et al.

Different SD-OCTs measure RNFL thickness differently, showing fixed and proportional biases. Instruments are not interchangeable, impacting glaucoma diagnosis and monitoring, as patient factors also affect agreement.

Leite Mauro T, Zangwill Linda M, Weinreb Robert N, Rao Harsha L, Alencar Luciana M, Sample Pamela A et al.

Cirrus OCT's glaucoma diagnostic accuracy was studied; it performs better in more severe disease. Clinicians should consider disease severity when interpreting OCT results.

Leite Mauro T, Alencar Luciana M, Gore Charlotte, Weinreb Robert N, Sample Pamela A, Zangwill Linda M et al.

This study found Black subjects have lower corneal hysteresis/resistance and thinner corneas than White subjects, but biomechanical differences largely disappear after adjusting for corneal thickness.

Leite Mauro T, Prata Tiago S, Kera Clarissa Z, Miranda Denise V, de Moraes Barros Silvia B, Melo Luiz As

This study found significantly reduced ascorbic acid in the secondary aqueous humor of glaucoma patients, suggesting a potential role for this antioxidant in post-surgical glaucoma management or disease progression.