Pang Chi-Pui

Chan Poemen PuiMan, Shen Ruyue, Cheung Carol Y, Ling Anni, Yu Marco, Pang Chi-Pui et al.

This study found normal tension glaucoma (NTG) shows faster peripapillary vessel density loss than primary angle closure glaucoma (PACG), suggesting distinct vascular contributions to NTG progression.

Liu Shu, Li Zhi-wai, Weinreb Robert N, Xu Guihua, Lindsey James D, Ye Cong et al.

This study tracked retinal microglia in mice after optic nerve injury, finding microgliosis correlates with RGC loss. This imaging method could help assess glaucoma progression and treatment efficacy.

Chen Jian-Huan, Wang Degui, Huang Chukai, Zheng Yuqian, Chen Haoyu, Pang Chi-Pui et al.

This study found that specific genetic variations in ATOH7 and RFTN1 genes, when combined, significantly increase the risk for primary open-angle glaucoma, highlighting complex genetic interactions in disease development.

Li Zhi-wai, Liu Shu, Weinreb Robert N, Lindsey James D, Yu Marco, Liu Lan et al.

This study found RGC dendrites progressively shrink after 90-120 minutes of acute high IOP, but not shorter durations. This suggests dendritic shrinkage is an early, measurable sign of RGC damage in glaucoma.

Jia Li-Yun, Gong Bo, Pang Chi-Pui, Huang Yao, Lam Dennis Shun-Chiu, Wang Ningli et al.

This study found a novel myocilin mutation causing juvenile glaucoma. A natural osmolyte, TMAO, improved the mutant protein's folding, secretion, and reduced cell stress. This suggests a potential chaperone-based therapy for myocilin-related glaucoma.

Leung Christopher Kai-Shun, Cheung Carol Yim-Lui, Weinreb Robert N, Qiu Quanliang, Liu Shu, Li Haitao et al.

This study compared two OCT devices for glaucoma detection. Cirrus HD-OCT showed lower RNFL measurement variability than Stratus OCT, but both had comparable diagnostic performance and structure-function association. This suggests Cirrus offers more precise RNFL tracking.

Cheung Carol Yim Lui, Leung Christopher Kai Shun, Lin Dusheung, Pang Chi-Pui, Lam Dennis Shun Chiu

OCT RNFL measurements vary significantly with signal strength. Higher signal strength generally yields thicker RNFL readings. Clinically, always optimize OCT signal strength for accurate glaucoma assessment.

Tong Jian-Ping, Chan Wai-Man, Liu David T L, Lai Timothy Y Y, Choy Kwong-Wai, Pang Chi-Pui et al.

This study found elevated aqueous VEGF and PEDF in PCV and CNV, but VEGF was lower in PCV than AMD, suggesting distinct disease mechanisms or angiogenesis courses.

Fan Bao-Jian, Leung Yuk-Fai, Pang Chi-Pui, Fan Dorothy S P, Wang Dan-Yi, Tong Wing-Chiu et al.

This study found myocilin gene promoter polymorphisms in Chinese patients are unrelated to primary open-angle glaucoma risk or severity, meaning they aren't useful diagnostic markers.